132981-94-3Relevant academic research and scientific papers
SUBSTITUTED PROPANAMIDES AS INHIBITORS OF NUCLEASES
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Page/Page column 11; 13; 23; 24; 26, (2019/11/12)
The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3, R4, R5, R6 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
Synthesis of 5-Phenylthiazolamines by Using Thiourea as an α-Bromination Shuttle
Roslan, Irwan Iskandar,Ng, Kian-Hong,Chuah, Gaik-Khuan,Jaenicke, Stephan
, p. 704 - 709 (2017/02/05)
A straightforward synthesis of 5-phenylthiazolamines by coupling thiourea with phenylacetones, phenylacetophenones, and β-tetralone has been developed. Thiourea acts as a substrate and an α-bromination shuttle by transferring a Br atom from CBrCl3/s
