1329834-12-9

Basic information

• Product Name: Idazoxan-d4 Hydrochloride
• Synonyms: Idazoxan-d4 Hydrochloride;(+/-)-Idazoxan-d4 Monohydrochloride;2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-iMidazole-d4 Hydrochloride;RX 781094A-d4;RX 781094-d4
• CAS NO: 1329834-12-9
• Molecular Formula: C11H13ClN2O2
• Molecular Weight: 240.68612
• Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals
• Mol File: 1329834-12-9.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Idazoxan-d4 Hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Idazoxan-d4 Hydrochloride(1329834-12-9)
• EPA Substance Registry System: Idazoxan-d4 Hydrochloride(1329834-12-9)

Safety Data

• Hazardous Substances Data: 1329834-12-9(Hazardous Substances Data)

Usage

Description

Idazoxan-d4 Hydrochloride, also known as Labelled Idazoxan (I506800), is a chemical compound that serves as an α-adrenoceptor antagonist. It is particularly effective in the rat brain, where it acts as a pure antagonist with a high selectivity for α2over α1-receptors. This selectivity is significantly greater than that of other compounds such as Piperoxane, Yohimbine, or Rauwolscine. Idazoxan-d4 Hydrochloride is also recognized for its potential antiparkinsonian properties.

Uses

Used in Pharmaceutical Industry:
Idazoxan-d4 Hydrochloride is used as a pharmaceutical compound for its α-adrenoceptor antagonist properties. It is particularly valuable in the treatment and management of various conditions related to the adrenergic system, such as hypertension and other cardiovascular diseases.
Used in Neurological Research:
Idazoxan-d4 Hydrochloride is used as a research tool for studying the role of α2-adrenergic receptors in the central nervous system. Its high selectivity for α2over α1-receptors makes it an ideal candidate for investigating the underlying mechanisms of various neurological disorders and their potential treatments.
Used in Antiparkinsonian Applications:
Idazoxan-d4 Hydrochloride is used as an antiparkinsonian agent, targeting the symptoms of Parkinson's disease by modulating the adrenergic system. Its ability to act as an α-adrenoceptor antagonist can help alleviate some of the motor and non-motor symptoms associated with the condition.
Used in Drug Development:
Idazoxan-d4 Hydrochloride is used as a lead compound in the development of new drugs targeting the adrenergic system. Its unique properties and selectivity make it a promising starting point for the design and synthesis of novel therapeutic agents for a range of conditions, including cardiovascular diseases, neurological disorders, and other related health issues.