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132996-61-3

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132996-61-3 Usage

General Description

Osteogenic growth peptide (OGP) is a naturally occurring 14-amino acid peptide that has been found to stimulate the development and regeneration of bone tissue. It works by binding to specific receptors on the surface of bone cells, effectively promoting the proliferation and differentiation of osteoblasts, which are the cells responsible for building new bone. Studies have shown that OGP can enhance bone formation, increase bone mineral density, and accelerate fracture healing. As a result, OGP is being investigated as a potential therapeutic agent for the treatment of osteoporosis, bone fractures, and other bone-related conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 132996-61-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,9,9 and 6 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 132996-61:
(8*1)+(7*3)+(6*2)+(5*9)+(4*9)+(3*6)+(2*6)+(1*1)=153
153 % 10 = 3
So 132996-61-3 is a valid CAS Registry Number.
InChI:InChI=1/C68H110N22O18/c1-36(2)28-47(87-57(99)38(5)70)64(106)85-44(16-10-11-25-69)61(103)84-45(18-13-27-77-68(74)75)62(104)86-46(23-24-51(71)93)58(100)80-33-53(95)82-43(17-12-26-76-67(72)73)63(105)90-56(39(6)91)66(108)89-48(29-37(3)4)65(107)88-50(31-41-19-21-42(92)22-20-41)60(102)81-34-54(96)83-49(30-40-14-8-7-9-15-40)59(101)79-32-52(94)78-35-55(97)98/h7-9,14-15,19-22,36-39,43-50,56,91-92H,10-13,16-18,23-35,69-70H2,1-6H3,(H2,71,93)(H,78,94)(H,79,101)(H,80,100)(H,81,102)(H,82,95)(H,83,96)(H,84,103)(H,85,106)(H,86,104)(H,87,99)(H,88,107)(H,89,108)(H,90,105)(H,97,98)(H4,72,73,76)(H4,74,75,77)/t38-,39+,43-,44-,45-,46-,47-,48-,49-,50-,56-/m0/s1

132996-61-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name D-Alanyl-L-leucyl-L-lysyl-L-arginyl-L-glutaminylglycyl-L-arginyl-L-allothreonyl-L-leucyl-D-tyrosylglycyl-N-benzylglycylglycylglycinamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:132996-61-3 SDS

132996-61-3Upstream product

132996-61-3Downstream Products

132996-61-3Related news

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Materials currently used for the treatment of bone defects include ceramics, polymeric scaffolds and composites, which are often impregnated with recombinant growth factors and other bioactive substances. While these materials have seen instances of success, each has inherent shortcomings includ...detailed

Nanostructured materials based on mesoporous silica and mesoporous silica/apatite as OSTEOGENIC GROWTH PEPTIDE (cas 132996-61-3) carriers09/05/2019

The aim of this work was the preparation of inorganic mesoporous materials from silica, calcium phosphate and a nonionic surfactant and to evaluate the incorporation and release of different concentrations of osteogenic growth peptide (OGP) for application in bone regeneration. The adsorption an...detailed

Novel OSTEOGENIC GROWTH PEPTIDE (cas 132996-61-3) C-terminal pentapeptide grafted poly(d,l-lactic acid) improves the proliferation and differentiation of osteoblasts: The potential bone regenerative biomaterial09/04/2019

Poly(d,l-lactic acid) (PDLLA) is widely used for bone regenerative engineering, because of its proven biocompatibility and biodegradability. However, the major limitation of PDLLA is its cell recognition and low hydrophilicity. The objective of this study was to develop a novel bioactive poly(d,...detailed

OSTEOGENIC GROWTH PEPTIDE (cas 132996-61-3) promotes osteogenic differentiation of mesenchymal stem cells mediated by LncRNA AK141205-induced upregulation of CXCL1309/01/2019

The aim of present study was to characterize long non-coding RNA (lncRNA) AK141205 as a cellular regulator of osteogenic differentiation of mice mesenchymal stem cells (MSCs) towards osteogenic growth peptide (OGP) stimulation. Mice MSCs cells were isolated, transfected with si-AK141205, pcDNA-A...detailed

Nanocellulose-collagen-apatite composite associated with OSTEOGENIC GROWTH PEPTIDE (cas 132996-61-3) for bone regeneration08/31/2019

Despite advances in the field of biomaterials for bone repair/regeneration, some challenges for developing an ideal bone substitute need to be overcome. Herein, this study synthesized and evaluated in vitro a nanocomposite based on bacterial cellulose (BC), collagen (COL), apatite (Ap) and osteo...detailed

Surface modification of TiO2 nanotubes with OSTEOGENIC GROWTH PEPTIDE (cas 132996-61-3) to enhance osteoblast differentiation08/30/2019

To investigate the influence of surface-biofunctionalized substrates on osteoblast behavior, a layer of aligned TiO2 nanotubes with a diameter of around 70 nm was fabricated on titanium surface by anodization, and then osteogenic growth peptide (OGP) was conjugated onto TiO2 nanotubes through th...detailed

Three-dimensional printing and in vitro evaluation of poly(3-hydroxybutyrate) scaffolds functionalized with OSTEOGENIC GROWTH PEPTIDE (cas 132996-61-3) for tissue engineering08/29/2019

Poly(3-hydroxybutyrate) (PHB) is a biodegradable and thermoprocessable biopolymer, making it a promising candidate for applications in tissue engineering. In the present study a structural characterization and in vitro evaluation were performed on PHB scaffolds produced by additive manufacturing...detailed

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