132996-61-3

Usage

Uses

Used in Orthopedics and Regenerative Medicine:
OSTEOGENIC GROWTH PEPTIDE is used as a therapeutic agent for promoting bone growth and regeneration. It is particularly beneficial for the treatment of osteoporosis, bone fractures, and other bone-related conditions due to its ability to enhance bone formation and increase bone mineral density.
Used in Drug Development for Bone Health:
OSTEOGENIC GROWTH PEPTIDE is used as a key component in the development of pharmaceuticals aimed at improving bone health and treating bone disorders. Its potential as a therapeutic agent is being investigated for its ability to accelerate fracture healing and promote bone tissue repair.
Used in Tissue Engineering and Biomaterials:
In the field of tissue engineering and biomaterials, OSTEOGENIC GROWTH PEPTIDE is used as a bioactive component incorporated into scaffolds and other engineered constructs to enhance bone tissue regeneration and integration. Its presence in these materials helps to stimulate the proliferation and differentiation of osteoblasts, thereby promoting the formation of new bone tissue.
Used in Research and Preclinical Studies:
OSTEOGENIC GROWTH PEPTIDE is used as a research tool in preclinical studies to investigate its potential effects on bone growth, regeneration, and healing. It is utilized in various in vitro and in vivo models to evaluate its efficacy and safety in treating bone-related conditions and to explore its underlying mechanisms of action.

InChI:InChI=1/C68H110N22O18/c1-36(2)28-47(87-57(99)38(5)70)64(106)85-44(16-10-11-25-69)61(103)84-45(18-13-27-77-68(74)75)62(104)86-46(23-24-51(71)93)58(100)80-33-53(95)82-43(17-12-26-76-67(72)73)63(105)90-56(39(6)91)66(108)89-48(29-37(3)4)65(107)88-50(31-41-19-21-42(92)22-20-41)60(102)81-34-54(96)83-49(30-40-14-8-7-9-15-40)59(101)79-32-52(94)78-35-55(97)98/h7-9,14-15,19-22,36-39,43-50,56,91-92H,10-13,16-18,23-35,69-70H2,1-6H3,(H2,71,93)(H,78,94)(H,79,101)(H,80,100)(H,81,102)(H,82,95)(H,83,96)(H,84,103)(H,85,106)(H,86,104)(H,87,99)(H,88,107)(H,89,108)(H,90,105)(H,97,98)(H4,72,73,76)(H4,74,75,77)/t38-,39+,43-,44-,45-,46-,47-,48-,49-,50-,56-/m0/s1

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Materials currently used for the treatment of bone defects include ceramics, polymeric scaffolds and composites, which are often impregnated with recombinant growth factors and other bioactive substances. While these materials have seen instances of success, each has inherent shortcomings includ...detailed

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The aim of present study was to characterize long non-coding RNA (lncRNA) AK141205 as a cellular regulator of osteogenic differentiation of mice mesenchymal stem cells (MSCs) towards osteogenic growth peptide (OGP) stimulation. Mice MSCs cells were isolated, transfected with si-AK141205, pcDNA-A...detailed

Nanocellulose-collagen-apatite composite associated with OSTEOGENIC GROWTH PEPTIDE (cas 132996-61-3) for bone regeneration08/31/2019

Despite advances in the field of biomaterials for bone repair/regeneration, some challenges for developing an ideal bone substitute need to be overcome. Herein, this study synthesized and evaluated in vitro a nanocomposite based on bacterial cellulose (BC), collagen (COL), apatite (Ap) and osteo...detailed

Surface modification of TiO2 nanotubes with OSTEOGENIC GROWTH PEPTIDE (cas 132996-61-3) to enhance osteoblast differentiation08/30/2019

To investigate the influence of surface-biofunctionalized substrates on osteoblast behavior, a layer of aligned TiO2 nanotubes with a diameter of around 70 nm was fabricated on titanium surface by anodization, and then osteogenic growth peptide (OGP) was conjugated onto TiO2 nanotubes through th...detailed

Three-dimensional printing and in vitro evaluation of poly(3-hydroxybutyrate) scaffolds functionalized with OSTEOGENIC GROWTH PEPTIDE (cas 132996-61-3) for tissue engineering08/29/2019

Poly(3-hydroxybutyrate) (PHB) is a biodegradable and thermoprocessable biopolymer, making it a promising candidate for applications in tissue engineering. In the present study a structural characterization and in vitro evaluation were performed on PHB scaffolds produced by additive manufacturing...detailed