1329991-41-4Relevant academic research and scientific papers
Optimization of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of HIV capsid assembly inhibitors 1: Addressing configurational instability through scaffold modification
Fader, Lee D.,Landry, Serge,Morin, Sébastien,Kawai, Stephen H.,Bousquet, Yves,Hucke, Oliver,Goudreau, Nathalie,Lemke, Christopher T.,Bonneau, Pierre,Titolo, Steve,Mason, Stephen,Simoneau, Bruno
, p. 3396 - 3400 (2013/06/27)
The optimization of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of inhibitors of HIV-1 capsid assembly that possess a labile stereocenter at C3 is described. Quaternization of the C3 position of compound 1 in order to prevent racemization gave co
DERIVATIVES OF 1-PHENYL-1,5-DIHYDRO-BENZO[B] [1.4]DIAZEPINE-2.4-DIONE AS INHIBITORS OF HIV REPLICATION
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, (2011/09/19)
Compounds of formula (I) wherein m, R1, R2, R3, X and Y are defined herein, are useful as inhibitors of HIV replication.
