133005-22-8Relevant articles and documents
N-trialkylsilyl Bistrifluoromethanesulfonimides (R3SiNTf 2) are powerful catalysts for the highly efficient α-amido alkylation reactions of silicon-based nucleophiles
Othman, Raja Ben,Bousquet, Till,Othman, Mohamed,Dalla, Vincent
, p. 5335 - 5337 (2007/10/03)
(Chemical Equation Presented) In situ formed N-trialkylsilyl bistrifluoromethanesulfonimides (R3SiNTf2) species have been shown to efficiently catalyze the nucleophilic substitution reactions of chiral 5-oxypyrrolidin-2-ones by silic
Toward improving the chemistry of N-acyliminium ions: Nucleophilic substitution reactions of pyrrolidinone derivatives with trialkylsilyl nucleophiles catalyzed by triisopropylsilyltrifluoromethane sulfonate (TIPSOTf)
Othman, Raja Ben,Bousquet, Till,Fousse, Anthony,Othman, Mohamed,Dalla, Vincent
, p. 2825 - 2828 (2007/10/03)
(Chemical Equation Presented) Nucleophilic substitution reactions of racemic and chiral 5-acetoxy-, 5-ethoxy-, and 5-methoxypyrrolidin-2-ones by silicon-based nucleophiles were efficiently catalyzed by TIPSOTf. This process was found to be general and acc
Addition of silylated carbon nucleophiles to iminium and cyclic N-acyliminium ions promoted by InCl3
Russowsky,Petersen,Godoi,Pilli
, p. 9939 - 9942 (2007/10/03)
InCl3 was used as Lewis acid in the addition of silyl enolates and allyltrimethylsilane to aromatic aldimines and cyclic N-acyliminium ions derived from 5-acetoxylactams affording β-aminocarbonyl systems and allyl adducts, respectively, in reas
SYNTHESIS OF STATINE FROM (S)-MALIC ACID; STEREOCONTROL VIA RADICAL CYCLIZATION
Koot, Wim-Jan,Ginkel, Roel van,Kranenburg, Mirko,Hiemstra, Henk,Louwrier, Saskia,et al.
, p. 401 - 404 (2007/10/02)
Highly stereoselective syntheses of enantiomerically pure γ-amino acids statine and 4-epi-statine from (S)-malic acid are described by using, respectively, an intramolecular α-acylamino radical reaction and an intermolecular N-acyliminium allylsilane coupling.
Stereoselective synthesis of statin analogues
Bernardi,Micheli,Potenza,Scolastico,Villa
, p. 4949 - 4952 (2007/10/02)
Statin analogues can be synthesized stereoselectively (diastereomeric ratios up to 4:1) starting from malic acid. The key step involves an unprecedented cis-selective allylation of an α-alkoxy N-acyliminium ion.