133010-20-5

Basic information

• Product Name: Cbz-Val-F
• Synonyms: Cbz-Val-F
• CAS NO: 133010-20-5
• Molecular Weight: 253.273
• Mol File: 133010-20-5.mol

Chemical Properties

• CAS DataBase Reference: Cbz-Val-F(CAS DataBase Reference)
• NIST Chemistry Reference: Cbz-Val-F(133010-20-5)
• EPA Substance Registry System: Cbz-Val-F(133010-20-5)

Safety Data

• Hazardous Substances Data: 133010-20-5(Hazardous Substances Data)

Upstream product

• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 

Downstream Products

• 25460-78-0 N-cbz-L-Val-L-Phe-OEt 
• 132682-04-3 methyl (S)-2-(2-(((benzyloxy)carbonyl)amino)-3-methylbutanamido)-2-methylpropanoate 
• 22221-83-6 benzyloxycarbonyl-L-valyl-L-alanine methyl ester 
• 1058149-08-8 C₂₄H₃₈N₄O₆ 
• 1058148-44-9 C₂₄H₃₆N₄O₅ 
• 55739-16-7 Z-L-Val-L-Ala-OEt 
• 2766-17-8 ethyl N-(benzyloxycarbonyl)-L-valylglycinate 

Relevant articles and documents

Metal-free approach for hindered amide-bond formation with hypervalent iodine(iii) reagents: application to hindered peptide synthesis

A new bio-inspired approach is reported for amide and peptide synthesis using α-amino esters that possess a potential activating group (PAG) at the ester residue. To activate the ester functionality under mild metal-free conditions, we exploited the facile dearomatization of phenols with hypervalent iodine(iii) reagents. Using a pyridine-hydrogen fluoride complex, highly reactive acyl fluoride intermediates can be successfully generated, thereby allowing for the smooth formation of sterically hindered amides and peptides from bulky amines and α-amino esters, respectively.

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