1330145-03-3Relevant articles and documents
Design and synthesis of a new series of cyclopropylamino-linking diarylpyrimidines as HIV non-nucleoside reverse transcriptase inhibitors
Liu, Yang,Meng, Ge,Zheng, Aqun,Chen, Fener,Chen, Wenxue,Clercq, Erik De,Pannecouque, Christophe,Balzarini, Jan
, p. 334 - 341 (2014/07/22)
A new series of 29 diarylpyrimidine analogues featuring a cyclopropylamino group between the pyrimidine scaffold and the aryl wing have been synthesized. All of the new compounds have been characterized by spectra analysis. The target molecules were evalu
Synthesis and structure-activity relationship of novel diarylpyrimidines with hydromethyl linker (CH(OH)-DAPYs) as HIV-1 NNRTIs
Gu, Shuang-Xi,He, Qiu-Qin,Yang, Shi-Qiong,Ma, Xiao-Dong,Chen, Fen-Er,Clercq, Erik De,Balzarini, Jan,Pannecouque, Christophe
, p. 5117 - 5124 (2011/10/04)
A series of 26 diarylpyrimidines, characterized by the hydroxymethyl linker between the left wing benzene ring and the central pyrimidine, were synthesized and evaluated for in vitro anti-HIV activity. Most of the compounds exhibited moderate to excellent
