133017-21-7

Upstream product

• 77-78-1 dimethyl sulfate 
• 195305-56-7 Bis-methylsulfanyl-phenyl-thioacetic acid S-methyl ester 
• 2912-62-1 α-chlorophenylacetyl chloride 
• 22946-46-9 methyl α-phenyl-α-methylthio-thioacetate 
• 74-88-4 methyl iodide 

Downstream Products

• 133017-17-1 2-Methanesulfinyl-2-phenyl-thiopropionic acid S-methyl ester 
• 22966-64-9 S-methyl α-(phenyl)thiopropionate 
• 492-37-5 hydratropic acid 

Relevant academic research and scientific papers

An interesting synthetic application of S-alkyl (aryl)bis(alkylsulfanyl)thioacetates: General procedure for the preparation of (±)-α-arylpropionic acids

Reported here is a new procedure for the synthesis of α-arylpropionic acids 1 in the racemic form, starting from derivatives of aromatic carboxylic acids 2 (i.e., esters), via 1-aryl-2,2,2-tris(alkylsulfanyl)ethanones 4-6, S-alkyl (aryl)bis(alkylsulfanyl)thioacetates 7-9, S-alkyl α-aryl-α-(alkylsulfanyl)thiopropionates 10-12 and S-alkyl α-arylthiopropionates 13-15. Each stage takes place easily and yields are always high.

New α-Sulfinyl-thioesters, as Precursors to Thioacrylates

Several substituted α-sulfinyl thioacetates, prepared by α-alkylation and α-sulfur oxidation methods, gave by thermal decomposition thioacrylates.