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133029-32-0

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133029-32-0 Usage

Uses

Polyhexamethylene biguanide (PHMB) is an antiseptic with antiviral and antibacterial properties used in several ways including wound care dressings, contact lens cleaning solutions, perioperative cleansing products, and swimming pool cleaners.

Definition

A hydrochloride salt of polyhexamethylene biguanide. It is a broad spectrum and fast acting bactericide which is used for the formulation of disinfectants and sanitisers.

Side effects

PHMB (polyaminopropyl biguanide) proved toxic to keratocytes and was shown to have acute toxic effects in human cells where it caused severe inflammation, atherogenesis, and aging.

Safety

Polyaminopropyl Biguanide (PHMB) is not safe for consumers when used as a preservative in all cosmetic products up to the maximum concentration of 0.3%. The safe use could be based on a lower use concentration and/or restrictions with regard to cosmetic products' categories.

Check Digit Verification of cas no

The CAS Registry Mumber 133029-32-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,0,2 and 9 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 133029-32:
(8*1)+(7*3)+(6*3)+(5*0)+(4*2)+(3*9)+(2*3)+(1*2)=90
90 % 10 = 0
So 133029-32-0 is a valid CAS Registry Number.

133029-32-0Upstream product

133029-32-0Downstream Products

133029-32-0Related news

CommentaryOpinion of the scientific committee on consumer safety (SCCS) – 2nd Revision of the safety of the use of poly(hexamethylene) biguanide hydrochloride or POLYAMINOPROPYL BIGUANIDE (cas 133029-32-0) (PHMB) in cosmetic products09/02/2019

Conclusion of the opinion: On the basis of the data available, the SCCS concludes that Polyaminopropyl Biguanide (PHMB) is not safe for consumers when used as a preservative in cosmetic spray formulations and in all cosmetic products up to the maximum concentration of 0.3%. The safe use could be...detailed

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