133038-82-1

Basic information

• Product Name: (4S,5R)-4-Benzyl-5-(1,1-difluoro-2-oxo-3-phenyl-propyl)-oxazolidin-2-one
• Synonyms: (4S,5R)-4-Benzyl-5-(1,1-difluoro-2-oxo-3-phenyl-propyl)-oxazolidin-2-one
• CAS NO: 133038-82-1
• Molecular Weight: 345.346
• Mol File: 133038-82-1.mol

Chemical Properties

• CAS DataBase Reference: (4S,5R)-4-Benzyl-5-(1,1-difluoro-2-oxo-3-phenyl-propyl)-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5R)-4-Benzyl-5-(1,1-difluoro-2-oxo-3-phenyl-propyl)-oxazolidin-2-one(133038-82-1)
• EPA Substance Registry System: (4S,5R)-4-Benzyl-5-(1,1-difluoro-2-oxo-3-phenyl-propyl)-oxazolidin-2-one(133038-82-1)

Safety Data

• Hazardous Substances Data: 133038-82-1(Hazardous Substances Data)

Upstream product

• 1589-82-8 phenylmagnesium bromide 
• 134450-42-3 2-((4S,5R)-4-Benzyl-2-oxo-oxazolidin-5-yl)-2,2-difluoro-N-methoxy-N-methyl-acetamide 
• 133038-81-0 ((4S,5R)-4-Benzyl-2-oxo-oxazolidin-5-yl)-difluoro-acetic acid ethyl ester 

Downstream Products

• 133038-83-2 (4S,5R)-5-((S)-2-Amino-1,1-difluoro-3-phenyl-propyl)-4-benzyl-oxazolidin-2-one 
• 133038-84-3 (4S,5R)-5-((R)-2-Amino-1,1-difluoro-3-phenyl-propyl)-4-benzyl-oxazolidin-2-one 
• 133038-86-5 (2S,3R,5S)-2,5-Diamino-4,4-difluoro-1,6-diphenyl-hexan-3-ol 
• 133099-35-1 (2S,3R,5R)-2,5-Diamino-4,4-difluoro-1,6-diphenyl-hexan-3-ol 
• 133038-87-6 {(S)-1-[(1S,3R,4S)-1-Benzyl-4-((S)-2-benzyloxycarbonylamino-3-methyl-butyrylamino)-2,2-difluoro-3-hydroxy-5-phenyl-pentylcarbamoyl]-2-methyl-propyl}-carbamic acid benzyl ester 
• 133099-36-2 {(S)-1-[(1R,3R,4S)-1-Benzyl-4-((S)-2-benzyloxycarbonylamino-3-methyl-butyrylamino)-2,2-difluoro-3-hydroxy-5-phenyl-pentylcarbamoyl]-2-methyl-propyl}-carbamic acid benzyl ester 
• 133038-85-4 {(S)-1-[(1S,4S)-1-Benzyl-4-((S)-2-benzyloxycarbonylamino-3-methyl-butyrylamino)-2,2-difluoro-3-oxo-5-phenyl-pentylcarbamoyl]-2-methyl-propyl}-carbamic acid benzyl ester 
• 144164-31-8 (4S,5R)-4-Benzyl-5-{1,1-difluoro-2-[(E)-hydroxyimino]-3-phenyl-propyl}-oxazolidin-2-one 

Relevant articles and documents

Synthesis of (2S,5S,4R)-2,5-Diamino-3,3-difluoro-1,6-diphenylhydroxyhexane: The Core Unit of a Potent HIV Proteinase Inhibitor

The coupling of the novel pseudo-symmetrical dipeptide mimic 1a, synthesized via Boc-L-phenylalaninol, with Z-L-valine led to a very potent inhibitor of the HIV proteinase.