133041-49-3

Basic information

• Product Name: 2-[2-hydroxyethyl-[4-[[4-(quinolin-4-ylamino)phenyl]methyl]phenyl]amin o]ethanol dihydrochloride
• Synonyms: 2-[2-hydroxyethyl-[4-[[4-(quinolin-4-ylamino)phenyl]methyl]phenyl]amin o]ethanol dihydrochloride
• CAS NO: 133041-49-3
• Molecular Formula: C26H29Cl2N3O2
• Molecular Weight: 0
• Mol File: 133041-49-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 645.8°Cat760mmHg
• Flash Point: 344.3°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 1.47E-17mmHg at 25°C
• CAS DataBase Reference: 2-[2-hydroxyethyl-[4-[[4-(quinolin-4-ylamino)phenyl]methyl]phenyl]amin o]ethanol dihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-hydroxyethyl-[4-[[4-(quinolin-4-ylamino)phenyl]methyl]phenyl]amin o]ethanol dihydrochloride(133041-49-3)
• EPA Substance Registry System: 2-[2-hydroxyethyl-[4-[[4-(quinolin-4-ylamino)phenyl]methyl]phenyl]amin o]ethanol dihydrochloride(133041-49-3)

Safety Data

• Hazardous Substances Data: 133041-49-3(Hazardous Substances Data)

Usage

Molecular structure

The compound has an ethanolamine backbone with various aromatic groups and a quinoline moiety attached.

Pharmacological properties

The compound has potential as an antineoplastic and antiviral agent, as it has been investigated for its ability to inhibit the growth and proliferation of cancer cells and viruses.

Diagnostic potential

The compound has been explored for its ability to bind to specific targets in the body, allowing for imaging and detection of certain diseases and conditions.

Research status

Further research is needed to fully understand and utilize the potential therapeutic applications of this compound.

InChI:InChI=1/C26H27N3O2.2ClH/c30-17-15-29(16-18-31)23-11-7-21(8-12-23)19-20-5-9-22(10-6-20)28-26-13-14-27-25-4-2-1-3-24(25)26;;/h1-14,30-31H,15-19H2,(H,27,28);2*1H

Upstream product

• 133041-54-0 (4-{4-[Bis-(2-chloro-ethyl)-amino]-benzyl}-phenyl)-quinolin-4-yl-amine; hydrochloride 

Relevant articles and documents

Hydrolysis and Alkylating Reactivity of Aromatic Nitrogen Mustards

Rate constants for the hydrolysis of a series of aromatic nitrogen mustards Ar-X-C6H4-N(CH2CH2Cl)2 (X = O, CH2, CONH, S, CO and SO2) in buffered aqueous acetone mixtures have been obtained using HPLC technique which allows evaluation of the rate constants for hydrolytic displacement of both chlorines in consecutive reactions.Hydrolysis has a general-base-catalysed component and is accompanied by external chloride ion return.An aziridinium ion intermediate is implicated in at least one pathway.The mustards also alkylate the nucleophiles thiourea and4-(4-nitrobenzyl)-pyridine (NBP) and again the aziridinium ion intermediate is involved since the kinetic behaviour rules out a direct SN2 pathway.