133042-79-2Relevant articles and documents
Role of Spacer and Address Components in Peptidomimetic δ Opioid Receptor Antagonists Related to Naltrindole
Portoghese, P. S.,Nagase, H.,MaloneyHuss, K. E.,Lin, C.-E.,Takemori, A. E.
, p. 1715 - 1720 (1991)
A series of heterocyclic analogues 2-5 related to naltrindole (1) (NTI) and 6-arylnaltrexone derivatives 6-8 were synthesized in order to determine the role of the spacer and the address moieties in conferring δ opioid receptor antagonist activity.The ben