13305-26-5

Upstream product

• 5453-80-5 5-Norbornene-2-carboxaldehyde 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 107276-01-7 (3-chloro-propyl)-(norborn-5-en-2-yl-phenyl-methyl)-ether 
• 13305-44-7 (bicyclo[2.2.1]heptan-2-yl)(phenyl)methanol 
• 93172-37-3 (1R,2S,3S,6S,7R)-5-Phenyl-4-oxa-tricyclo[4.2.1.0^3,7]nonan-2-ol 
• 37794-89-1 bicyclo[2.2.1]heptan-2-yl(phenyl)methanone 
• 115080-62-1 diethyl-[3-(norborn-5-en-2-yl-phenyl-methoxy)-propyl]-amine 
• 6056-35-5 endo/exo-bicyclo[2.2.1]hept-5-en-2-yl(phenyl)methanone 
• 1889-46-9 dimethyl-[2-(norborn-5-en-2-yl-phenyl-methoxy)-ethyl]-amine 

Relevant academic research and scientific papers

Rhodium-Catalyzed Remote Isomerization of Alkenyl Alcohols to Ketones

We develop herein an efficient rhodium-catalyzed remote isomerization of aromatic and aliphatic alkenyl alcohols into ketones. This catalytic process, with a commercially available catalyst and ligand ([RhCl(cod)]2 and Xantphos), features high efficiency, low catalyst loading, good functional group tolerance, a broad substrate scope, and no (sub)stoichiometric additive. Preliminary mechanistic studies suggest that this transformation involves an iterative dissociative β-hydride elimination-migration insertion process.

SILICON-BASED CROSS COUPLING AGENTS AND METHODS OF THEIR USE

Compositions and methods using silicon-based cross-coupling agents in the formation of carbon-carbon and carbon-nitrogen bonds are described.