1330539-97-3Relevant academic research and scientific papers
Antiproliferative activity of 2,3-disubstituted indoles toward apoptosis-resistant cancers cells
Magedov, Igor V.,Lefranc, Florence,Frolova, Liliya V.,Banuls, Laetitia Moreno Y.,Peretti, Amanda S.,Rogelj, Snezna,Mathieu, Veronique,Kiss, Robert,Kornienko, Alexander
, p. 3277 - 3282 (2013/06/27)
Many types of cancer, including glioma, melanoma, NSCLC, among others, are resistant to apoptosis induction and poorly responsive to current therapies with propaptotic agents. We describe a series of 2,3-disubstituted indoles, which display cytostatic rat
Unprecedented C-2 arylation of indole with diazonium salts: Syntheses of 2,3-disubstituted indoles and their antimicrobial activity
Daly, Seth,Hayden, Kathryn,Malik, Indranil,Porch, Nikki,Tang, Hong,Rogelj, Snezna,Frolova, Liliya V.,Lepthien, Katrina,Kornienko, Alexander,Magedov, Igor V.
, p. 4720 - 4723 (2011/09/16)
A novel reaction of indole with aryldiazonium salts leading to the formation of 2-aryl-3-(arylazo)indoles was discovered. The products were found to possess potent anti-MRSA and anti-LLVRE activities. The SAR studies indicate that the potentially metaboli
