133060-80-7

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Basic information

Product Name: 4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE
Synonyms: ZD 7288;4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE;N-Ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl-4-Pyrimidinamine;4-(N-Ethyl-N-phenylamino)-1,2 dimethyl-6-(methylamino) pyrimidinium chloride;ZD7288 hydrate
CAS NO:133060-80-7
Molecular Formula: C15H21ClN4
Molecular Weight: 292.81
EINECS: N/A
Product Categories: Ion transporter and other ion channel
Mol File: 133060-80-7.mol
Article Data: 1

Chemical Properties

Melting Point: N/A
Boiling Point: 359.9±52.0 °C(Predicted)
Flash Point: N/A
Appearance: white to beige/
Density: 1.04±0.1 g/cm3(Predicted)
Refractive Index: N/A
Storage Temp.: 2-8°C
Solubility: DMSO: soluble10mg/mL, clear
PKA: 11.97±0.70(Predicted)
CAS DataBase Reference: 4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE(CAS DataBase Reference)
NIST Chemistry Reference: 4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE(133060-80-7)
EPA Substance Registry System: 4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE(133060-80-7)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany: 3
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 133060-80-7(Hazardous Substances Data)

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Cas No: 133060-80-7
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Zhuozhou Wenxi import and Export Co., Ltd
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4-Pyrimidinamine,N-ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl-
Cas No: 133060-80-7
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Hangzhou J&H Chemical Co., Ltd.
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4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDECAS
Cas No: 133060-80-7
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Hangzhou Fandachem Co.,Ltd
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4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE
Cas No: 133060-80-7
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ZHEJIANG JIUZHOU CHEM CO.,LTD
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4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE
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Finetech Industry Limited
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4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE
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Wuxi Morality Chemical Co., Ltd
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4-Ethylphenylamino-1,2-dimethyl-6-methylaminopyrimidiniumchloride
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Debye Scientific
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6-ethyl-4-N,2,3-trimethyl-5-N-phenylpyrimidin-3-ium-4,5-diamine,chloride
Cas No: 133060-80-7
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NovaChemistry
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133060-80-7 Usage

Uses

ZD7288 hydrate has been used as?Ih?blocker to study its effect on neocortical tissue. It has been used as hyperpolarization-activated and cyclic nucleotide-gated (HCN)-channel blocker to test the involvement of HCN channels in the phototransduction pathway.

Biochem/physiol Actions

Selective blocker of cation channel Ih; If blocker and sino-atrial node function modulator, blocks hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels.

Check Digit Verification of cas no

The CAS Registry Mumber 133060-80-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,0,6 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 133060-80:
(8*1)+(7*3)+(6*3)+(5*0)+(4*6)+(3*0)+(2*8)+(1*0)=87
87 % 10 = 7
So 133060-80-7 is a valid CAS Registry Number.

InChI:InChI=1/C15H20N4.ClH/c1-5-12-8-6-7-9-13(12)18-14-10-15(16-3)19(4)11(2)17-14;/h6-10H,5H2,1-4H3,(H,16,18);1H

133060-80-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name	6-ethyl-4-N,2,3-trimethyl-5-N-phenylpyrimidin-3-ium-4,5-diamine,chloride

1.2 Other means of identification

Product number	-
Other names	4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:133060-80-7 SDS

133060-80-7Upstream product

133059-95-7 1,2-dimethyl-6-methylamino-4-N-ethylanilinopyrimidinium iodide

133060-80-7Downstream Products

133060-80-7Relevant articles and documents

Pyrimidine derivatives

-

, (2008/06/13)

This invention concerns novel aminopyrimidinium salts of the formula I: STR1 in which R1 is alkyl, alkenyl, cycloalkyl, phenyl, phenylalkyl or cycloalkyl-alkyl; one of R2 and R6 is a basic group selected from amino, alkyla

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