1330632-46-6

Basic information

• Product Name: 4-(2-Methylpropoxy)-1,3-benzenedicarbothioaMide
• Synonyms: 4-(2-Methylpropoxy)-1,3-benzenedicarbothioaMide;4-isobutoxybenzene-1,3-bis(carbothioamide);Febuxostat Impurity O
• CAS NO: 1330632-46-6
• Molecular Formula: C12H16N2OS2
• Molecular Weight: 268.39824
• Product Categories: Aromatics, Heterocycles, Pharmaceuticals, Intermediate, & Fine Chemicals
• Mol File: 1330632-46-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 451.2±55.0 °C(Predicted)
• Appearance: /
• Density: 1.239±0.06 g/cm3(Predicted)
• PKA: 12.46±0.29(Predicted)
• CAS DataBase Reference: 4-(2-Methylpropoxy)-1,3-benzenedicarbothioaMide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Methylpropoxy)-1,3-benzenedicarbothioaMide(1330632-46-6)
• EPA Substance Registry System: 4-(2-Methylpropoxy)-1,3-benzenedicarbothioaMide(1330632-46-6)

Safety Data

• Hazardous Substances Data: 1330632-46-6(Hazardous Substances Data)

Usage

Description

4-(2-Methylpropoxy)-1,3-benzenedicarbothioamide is an organic compound characterized by its chemical structure that features a benzene ring with two carbothioamide groups attached to the 1 and 3 positions, and a 2-methylpropoxy group attached to the 4 position. 4-(2-Methylpropoxy)-1,3-benzenedicarbothioaMide is known for its presence as an impurity in certain pharmaceuticals.

Uses

Used in Pharmaceutical Industry:
4-(2-Methylpropoxy)-1,3-benzenedicarbothioamide is used as an impurity in the urate-lowering drug Febuxostat (F229000). Febuxostat is an inhibitor of xanthine oxidase, which is indicated for the treatment of hyperuricemia and chronic gout. The presence of this compound in Febuxostat may affect the drug's efficacy and safety, and thus, its control and management are essential in the pharmaceutical manufacturing process.