133095-58-6

Upstream product

• 871706-30-8 (S)-2,2-dimethyl-4-(prop-1-yn-1-yl)-1,3-dioxolane 
• 133095-72-4 (S)-pent-3-yne-1,2-diol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 500596-47-4 (S)-5,5-dimethyl-octa-2,7-diynoic acid 1-(toluene-4-sulfonyloxymethyl)-but-2-ynyl ester 
• 133117-03-0 (S)-3-Methylene-4-((E)-propenyl)-pyrrolidine 
• 133095-59-7 Toluene-4-sulfonic acid (S)-2-(tert-butyl-dimethyl-silanyloxy)-pent-3-ynyl ester 

Relevant academic research and scientific papers

Palladium catalyzed cyclizations of enantiomerically pure acyclic 4-acetoxy-2,8-nonadienes: Efficient chirality transfer

S-4-Acetoxy-6-aza-2,8-nonadienes 9 and 11 were subjected to Pd(0)-catalyzed cyclizations. The S,E-acetate 9 gave exclusively S,E-pyrrolidine 12, whereas the antipodal product R,E-12 was formed from the S,Z-precursor 11 (Scheme 3). X-ray-diffraction analys

First total synthesis of the marine illudalane sesquiterpenoid alcyopterosin E.

The first synthesis of the marine illudalane sesquiterpenoid alcyopterosin E was accomplished through a concise ABC ring-formation strategy using a rhodium(I)-catalysed intramolecular alkyne cyclotrimerisation as key connection.