133098-04-1 Usage
Description
R-(-)-Isoflurane, also known as (R)-Isoflurane, is a chiral halogenated ether that serves as a potent inhalational anesthetic agent. It is characterized by its ability to induce and maintain anesthesia in a controlled manner, providing a stable and safe environment for surgical procedures.
Used in Medical Industry:
R-(-)-Isoflurane is used as an inhalational anesthetic agent for inducing and maintaining anesthesia during surgical procedures. It is favored for its rapid onset, controllable depth of anesthesia, and quick recovery time, making it suitable for a wide range of surgeries.
However, recent studies have raised concerns about a potential relationship between the administration of R-(-)-Isoflurane and postoperative cognitive dysfunction (POCD). This association warrants further investigation to ensure patient safety and optimize anesthetic choices.
Check Digit Verification of cas no
The CAS Registry Mumber 133098-04-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,0,9 and 8 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 133098-04:
(8*1)+(7*3)+(6*3)+(5*0)+(4*9)+(3*8)+(2*0)+(1*4)=111
111 % 10 = 1
So 133098-04-1 is a valid CAS Registry Number.
133098-04-1Relevant articles and documents
Preparation of the Isoflurane Enantiomers
Huang, Chialang G.,Rozov, Leonid A.,Halpern, Donald F.,Vernice, Gerald G.
, p. 7382 - 7387 (2007/10/02)
The enantiomers of the inhalation anesthetic agent, isoflurane (1-chloro-2,2,2-trifluoroethyl difluoromethyl ether), are prepared by a synthesis starting from 2,2,2-trifluoroethanol. (R)-(+)-Dehydroabietylamine is used as the resolving agent for the racemic acid intermediate 1.The optical purities of both (S)-(+)- and (R)-(-)-isofluranes are determined to be >99percent ee (enantiomeric excess) by chiral capillary gas chromatography.
