133125-15-2Relevant academic research and scientific papers
REACTIONS OF FLUOROBENZENE TRICARBONYLCHROMIUM COMPLEXES WITH ANIONS FROM SCHIFF BASES OF α-AMINO ESTERS; ENANTIOSELECTIVE SYNTHESIS OF α-ARYL AMINO ACIDS
Chaari, Mohamed,Jenhi, Aicha,Lavergne, Jean-Pierre,Viallefont, Philippe
, p. 4619 - 4630 (2007/10/02)
We report here a convenient synthesis of α-substituted aryl amino acids via the addition of α-imino esters to fluorobenzene tricarbonylchromium complexes.Optically pure α-aryl amino acids have been prepared by enantioselective substitution of fluorobenzene complexes using Schiff bases of L-alanine, leucine and valine methyl esters and (1R,2R,5R)-2-hydroxypinan-3-one.
Synthese enantioselective d'α-aryl amino acides: subtitution nucleophile aromatique sur le fluorobenzene chrome tricarbonyle d'enolates chiraux
Chaari, M.,Jenhi, A.,Lavergne, J.-P.,Viallefont, Ph.
, p. C10 - C13 (2007/10/02)
We report here a convenient synthesis of optically pure α-aryl amino acids by enantioselective substitution of fluorobenzene tricarbonylchromium using the Schiff bases of L-alanine methyl ester with (1R,2R,5R)-2-hydroxy-3-pinanone in presence of LDA or deprotonated 2-(tert-butyl)-4-methyl-1,3-oxazolidin-5 one.
