133128-41-3Relevant academic research and scientific papers
Enantioselective syntheses of α-Fmoc-Pbf-[2-13C]-L- arginine and Fmoc-[1,3-13C2]-L-proline and incorporation into the neurotensin receptor 1 ligand, NT8-13
Song, Chuanjun,Tapaneeyakorn, Satita,Murphy, Annabel C.,Butts, Craig,Watts, Anthony,Willis, Christine L.
scheme or table, p. 8980 - 8987 (2010/03/02)
(Chemical Equation Presented) Enantioselective syntheses of selectively labeled, orthogonally protected [2-13C]-L-arginine and [1,3- 13C2]-L-proline are described from the commercially available precursors [2-13C]bromoacetic acid and potassium [ 13C]cyanide. Interestingly the enhanced signal assigned to C-2 in the 13C NMR spectrum of α-Fmoc-Pbf-[2-13C]-L-arginine was very broad at room temperature. The two Fmoc-labeled amino acids were used to prepare [2-13C]-Arg9 and [1,3-13C2]-Pro10 labeled ligand (NT8-13) by manual Fmoc-SPSS.
Generation of [β-(phenylsulfonyl)alkylidene]carbenes from hypervalent alkenyl- and alkynyliodonium tetrafluoroborates and synthesis of 1-(phenylsulfonyl)cyclopentenes
Ochiai, Masahito,Kunishima, Munetaka,Tani, Shohei,Nagao, Yoshimitsu
, p. 3135 - 3142 (2007/10/02)
Michael-type addition of benzenesulfinic acid to alkynyl(phenyl)iodonium tetrafluoroborates in methanol gives stereoselectively (Z)-(β-(phenylsulfonyl)alkenyl)iodonium tetrafluoroborates in high yields. [β-(Phenylsulfonyl)alkylidene]carbenes derived from
