133145-15-0

Basic information

• Product Name: 6-CHLOROPYRIDINE-2-SULFONIC ACID
• Synonyms: 6-CHLOROPYRIDINE-2-SULFONIC ACID;6-CHLOROPYRIDINE-2-SULPHONIC ACID;6-Chloropyridine-2-sulfonicacid98%;6-CHLORO-2-PYRIDINESULFONIC ACID;6-CHLOROPYRIDINE-2-SULFONIC ACID 98%;2-Chloro-6-sulphopyridine
• CAS NO: 133145-15-0
• Molecular Formula: C₅H₄ClNO₃S
• Molecular Weight: 193.61
• Product Categories: Pyridines
• Mol File: 133145-15-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.649
• Refractive Index: 1.592
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-CHLOROPYRIDINE-2-SULFONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLOROPYRIDINE-2-SULFONIC ACID(133145-15-0)
• EPA Substance Registry System: 6-CHLOROPYRIDINE-2-SULFONIC ACID(133145-15-0)

Safety Data

• Hazard Codes: C
• Hazardous Substances Data: 133145-15-0(Hazardous Substances Data)

Usage

General Description

6-Chloropyridine-2-sulfonic Acid, also known as 6-CPSA, is a type of chemical compound used mainly in the field of chemistry and pharmaceuticals. It is an organosulfur compound, an organochlorine compound and a monosulfonic acid characterized by its unique molecular structure consisting of a pyridine ring with a chlorine atom at the 6th position and sulfonic acid at the 2nd position. The presence of chloropyridines in this compound makes it versatile in various syntheses and reactions. However, like various chemicals, it calls for safe handling and specific storage conditions to prevent health hazards. Its potential applications are still being researched particularly in the development of new drugs.

InChI:InChI=1/C5H4ClNO3S/c6-4-2-1-3-5(7-4)11(8,9)10/h1-3H,(H,8,9,10)

Upstream product

• 2402-78-0 2,6-dichloropyridine 
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• 130409-72-2 N-Fluoro-6-chloropyridinium-2-sulfonate 
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Relevant articles and documents

Synthesis and Properties of N-Fluoropyridinium Salts

Various stable N-fluoropyridinium salts with a non- or weakly nucleophilic counter anion such as TfO-, FSO3-, BF4-, ClO4-, CH3SO3- etc., or with an electron-donating or -withdrawing substituent(s) on the pyridine ring were synthesized and their properties investigated.N-Fluoropyridinium-2-sulfonates, N-fluoroquinolinium triflate, and highly hindered N-fluoro-2,6-di-t-butylpyridinium salts were also synthesized.They were synthesized by counter anion displacement reactions of unstable pyridine-F2 conpounds, fluorination of salts of pyridines with protonic acids or silyl esters with F2, and/or fluorination of Lewis acid complexes of pyridines.The scope of each method was examined in detail.Each of the N-fluoropyridinium salts was assigned as the first stable 1:1 salt structure of the pyridine nucleus and halogen atom on the basis of the spectral and elemental analysis.The stability depended on the nucleophilicity or basicity of the counter anions and electronic nature or position of the ring substituents.These results and NMR analyses clearly showed the unstable pyridine-F2 compounds to have N-fluoropyridinium fluoride salt structure.Some N-fluoropyridinium triflates were hydrolyzed and the products were examined, suggesting a unique hydrolysis mechanism.