133147-34-9

Basic information

• Product Name: (1S*,2R*,5R*)-2-n-butyl-5-hydroxymethyl-cyclohex-3-en-1-ol
• CAS NO: 133147-34-9
• Molecular Weight: 184.279
• Mol File: 133147-34-9.mol

Chemical Properties

• CAS DataBase Reference: (1S*,2R*,5R*)-2-n-butyl-5-hydroxymethyl-cyclohex-3-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S*,2R*,5R*)-2-n-butyl-5-hydroxymethyl-cyclohex-3-en-1-ol(133147-34-9)
• EPA Substance Registry System: (1S*,2R*,5R*)-2-n-butyl-5-hydroxymethyl-cyclohex-3-en-1-ol(133147-34-9)

Safety Data

• Hazardous Substances Data: 133147-34-9(Hazardous Substances Data)

Upstream product

• 109-72-8 n-butyllithium 
• 89898-05-5 7-oxabicyclo<2.2.1>hept-5-en-2-exo-ylmethanol 
• 89898-05-5 (1RS,2SR,4RS)-7-oxabicyclo[2.2.1]hept-5-ene-2-methanol 

Relevant articles and documents

RING-OPENING SN2' REACTIONS OF 7-OXANORBORNENES BY ORGANOLITHIUM REAGENTS. REGIO- AND STEREOSPECIFIC SYNTHESIS OF SUBSTITUTED CYCLOHEXENEDIOLS

The nucleophilic SN2' bridge opening of 7-oxabicyclohept-5-en-2-ols with organolithium reagents occurs in a regio- and stereospecific fashion to produce 6-substituted-cyclohex-4-en-1,3-diols, regardless of the stereochemistry at C-2.A free alcohol functionality is necessary to attain complete regiocontrol of the process.The methodology is utilized to prepare an optically pure cyclohexene derivative, (+)-(1S,3S,6R)-6-n-butyl-3-methyl-cyclohex-4-en-1,3-diol (5b), as a model system.