13315-71-4

Usage

Uses

Used in Organic Synthesis:
2,4-DIMETHYL-A-CARBOLINE is used as a synthetic intermediate for the development of various organic compounds. Its unique structure and chemical properties make it a valuable building block in the synthesis of complex organic molecules, which can be utilized in a wide range of applications, including pharmaceuticals, agrochemicals, and materials science.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,4-DIMETHYL-A-CARBOLINE is used as a key component in the synthesis of certain drugs and drug candidates. Its unique chemical properties allow it to form stable bonds with other molecules, making it an essential component in the development of new therapeutic agents.
Used in Agrochemical Industry:
2,4-DIMETHYL-A-CARBOLINE also finds applications in the agrochemical industry, where it is used as a precursor for the synthesis of various agrochemicals, such as pesticides and herbicides. Its ability to form stable bonds with other molecules makes it a valuable component in the development of effective and environmentally friendly agrochemicals.
Used in Materials Science:
In the field of materials science, 2,4-DIMETHYL-A-CARBOLINE is used as a component in the development of advanced materials with unique properties. Its ability to form stable bonds with other molecules allows it to be incorporated into the structure of various materials, resulting in improved performance and functionality.

InChI:InChI=1/C13H12N2/c1-8-7-9(2)14-13-12(8)10-5-3-4-6-11(10)15-13/h3-7H,1-2H3,(H,14,15)

Upstream product

• 1067492-43-6 4-(1H-indol-3-yl)pentan-2-one O-acetyl oxime 
• 1497420-59-3 tert-butyl 3-((2E)-4-(methoxyimino)pent-2-en-2-yl)-1H-indole-1-carboxylate 
• 124688-00-2 1-(3-(1-tert-butoxycarbonyl)indolyl)-1-ethanone 
• 703-80-0 3-acetylindole 

Relevant academic research and scientific papers

Synthesis of α-carbolines from β-(3-indolyl) ketone 0-2,4-dinitrophenyloximes

α-Carbolines are synthesized from β-(3-indolyl) ketone O-2,4-dinitrophenyloximes by the treatment with sodium hydride and sodium cyanoborohydride.

A new route to α-carbolines based on 6π-electrocyclization of indole-3-alkenyl oximes

Indoles are converted into α-carbolines in four steps by acylation at C-3, Boc-protection, olefination of the resulting 3-indolyl aldehydes or ketones to give N-Boc-3-indolyl alkenyl oxime O-methyl ethers, which upon heating to 240 C under microwave irradiation undergo loss of the Boc-group, and 6π-electrocyclization to α-carbolines, following aromatization by loss of methanol (11 examples, 30-90% yield).

Thermal rearrangement of indolyl oxime esters to pyridoindoles

(Chemical Equation Presented) Acyl oximes derived from a variety of indolylalkanones underwent a ring closure sequence during FVP to afford 9H-pyrido[2,3-b]indoles. Unlike UV light promoted reactions of oxime esters, the mechanism is almost certainly not mediated by iminyl radicals but probably involves tautomerism, elimination of acetic acid, and a final electrocyclic ring closure.

Arylacetamides and their use as medicaments

The new arylacetamides are obtained by first converting appropriately substituted arylacetic acids into the acetyl chlorides and then converting these into the amides using the appropriate amines. The new arylacetamides can be used as active compounds in medicaments, in particular in antiatherosclerotic medicaments.

Amides and sulphonamides of benzylamines having heterocyclic substituents

Amides and sulphonamides of benzylamines having heterocyclic substituents are prepared by first converting the corresponding carboxylic acids into the corresponding amines and then substituting these on the amine nitrogen in a corresponding manner. The new amides and sulphonamides of benzylamines having heterocyclic substituents can be used as active compounds in medicaments, in particular in antiatherosclerotic medicaments.

Cycloalkano-indole and -azaindole derivatives

Cycloalkano-indole and -azaindole derivatives are prepared by reaction of appropriately substituted carboxylic acids with amines. The cycloalkano-indole and -azaindole derivatives are suitable as active compounds for medicaments, preferably antiatheroscle