133157-91-2Relevant academic research and scientific papers
Compositions and Methods for Cellular Imaging and Therapy
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Page/Page column 39, (2008/06/13)
The present invention relates generally to the fields of chemistry and radionuclide imaging. More particularly, it concerns compositions, kits and methods for imaging and therapy involving N4 compounds and derivatives.
Halogenated analogues of tamoxifen: Synthesis, receptor assay, and inhibition of MCF7 cells
Yang,Tewson,Tansey,Kuang,Reger,Cherif,Wright,Moult,Tilbury,Chu,Kim,Wallace
, p. 622 - 625 (2007/10/02)
This study was conducted to develop a ligand for imaging estrogen- receptor-positive breast tumors by positron emission tomography or single photon emission computed tomography. We synthesized fluoro and iodo analogues of tamoxifen, and these halogenated
N,N-Diethylfluoromethyltamoxifen: Synthesis, assignment of 1H and 13C spectra and receptor assay
Yang,Cherif,Tansey,Kuang,Li,Wright,Kim,Wallace
, p. 919 - 924 (2007/10/02)
(cis) and (trans)N,N-diethylfluoromethyltamoxifen (1-[4-(2-diethylaminoethoxy)phenyl]-1,2-diphenyl-5-fluoro-1-pentene) were synthesized from clomiphene in a three-step procedure and both isomers were differentiated by the concerted application of two-dime
