1331670-10-0 Usage
Description
2-AMino-α-(MethoxyiMino)-4-thiazoleacetic Acid-d3 Methyl Ester is a deuterated compound that serves as an intermediate in the preparation of labeled Cephem compounds. It is a yellow solid with unique chemical properties that make it valuable in the field of pharmaceuticals and biochemistry.
Uses
Used in Pharmaceutical Industry:
2-AMino-α-(MethoxyiMino)-4-thiazoleacetic Acid-d3 Methyl Ester is used as an intermediate for the synthesis of labeled Cephem compounds, which are essential in the development of antibiotics. Its deuterated nature provides unique properties that can enhance the stability and effectiveness of these compounds, making it a valuable asset in the fight against bacterial infections.
Used in Biochemical Research:
In the field of biochemistry, 2-AMino-α-(MethoxyiMino)-4-thiazoleacetic Acid-d3 Methyl Ester can be employed as a research tool to study the behavior of Cephem compounds and their interactions with biological systems. Its deuterated form allows for the investigation of various biochemical processes, such as enzyme activity and metabolic pathways, providing valuable insights into the development of new drugs and therapies.
Used in Drug Development:
2-AMino-α-(MethoxyiMino)-4-thiazoleacetic Acid-d3 Methyl Ester can also be utilized in the development of new drugs, particularly in the area of antibiotics. Its unique properties can contribute to the design and synthesis of novel Cephem-based compounds with improved pharmacological profiles, potentially leading to the discovery of more effective treatments for bacterial infections.
Check Digit Verification of cas no
The CAS Registry Mumber 1331670-10-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,3,1,6,7 and 0 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1331670-10:
(9*1)+(8*3)+(7*3)+(6*1)+(5*6)+(4*7)+(3*0)+(2*1)+(1*0)=120
120 % 10 = 0
So 1331670-10-0 is a valid CAS Registry Number.
1331670-10-0Relevant articles and documents
Cefpodoxime D3 synthesis method
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, (2020/07/12)
The invention provides a cefpodoxime D3 synthesis method, which comprises: 1) carrying out an addition elimination reaction on a compound 1 and sodium nitrite to prepare a compound 2; 2) performing halogenation reaction on the compound 2 and liquid bromine to obtain a compound 3; 3) performing cyclization reaction on the compound 3 and thiourea to obtain a compound 4; 4) performing substitution reaction on the compound 4 and deuterated methyl iodide to obtain a compound 5; 5) carrying out hydrolysis reaction on the compound 5 and sodium hydroxide to prepare a compound 6; 6) performing ester condensation reaction on the compound 6 and dibenzothiazyl disulfide to obtain a compound 7, and 7) performing aminolysis reaction on sulfydryl ester on the compound 7 and the compound 8 to obtain cefpodoxime D3. According to the method, the intermediate compound 6 is synthesized by adopting commercially available deuterated methyl iodide for the first time, and then the final product of cefpodoximeD3 is successfully synthesized.
