1331742-81-4Relevant articles and documents
Hit to lead evaluation of 1,2,3-triazolo[4,5-b]pyridines as PIM kinase inhibitors
Pastor, Joaquín,Oyarzabal, Julen,Saluste, Gustavo,Alvarez, Rosa María,Rivero, Virginia,Ramos, Francisco,Cendón, Elena,Blanco-Aparicio, Carmen,Ajenjo, Nuria,Cebriá, Antonio,Albarrán,Cebrián, David,Corrionero, Ana,Fominaya, Jesús,Montoya, Guillermo,Mazzorana, Marco
, p. 1591 - 1597 (2012/04/10)
PIM kinases have become targets of interest due to their association with biochemical mechanisms affecting survival, proliferation and cytokine production. 1,2,3-Triazolo[4,5-b]pyridines were identified as PIM inhibitors applying a scaffold hopping approa
