133176-01-9Relevant academic research and scientific papers
Synthesis of Pyrazoloquinolines from 4-Aroyl-5-chloropyrazoles
Hennig, L.,Mueller, T.,Grosche, M.
, p. 693 - 698 (2007/10/02)
The reaction of 4-aroyl-5-chloro-3-methyl-1-phenyl-pyrazoles 1 with an excess of 3- or 4-substituted and 3,4-disubstituted anilines 2 gives pyrazoloquinolines 4a-k.Information about the reaction mechanism was obtained by the isolation of the intermediate product 3e.In some cases it was possible to isolate subsequent products 4l-p.The reaction of 1a with 5-amino-3-methyl-1-phenyl-pyrazole (5) gives a bispyrazolopyridine derivative 6.
