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13318-09-7

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13318-09-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 13318-09-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,3,1 and 8 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 13318-09:
(7*1)+(6*3)+(5*3)+(4*1)+(3*8)+(2*0)+(1*9)=77
77 % 10 = 7
So 13318-09-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H10O4/c1-6(2)7(9)11-5-10-4-3-8/h3H,1,4-5H2,2H3

13318-09-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-oxoethoxymethyl 2-methylprop-2-enoate

1.2 Other means of identification

Product number -
Other names 2-Propenoic acid,2-methyl-,2-methoxy-2-oxoethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13318-09-7 SDS

13318-09-7Downstream Products

13318-09-7Relevant articles and documents

Tailor-Made pH-Responsive Poly(choline phosphate) Prodrug as a Drug Delivery System for Rapid Cellular Internalization

Wang, Wenliang,Wang, Bo,Ma, Xiaojing,Liu, Sanrong,Shang, Xudong,Yu, Xifei

, p. 2223 - 2232 (2016)

Rapid cellular uptake and efficient drug release in tumor cells are two of the major challenges for cancer therapy. Herein, we designed and synthesized a novel pH-responsive polymer-drug conjugate system poly(2-(methacryloyloxy)ethyl choline phosphate)-b-poly(2-methoxy-2-oxoethyl methacrylate-hydrazide-doxorubicin) (PCP-Dox) to overcome these two challenges simultaneously. It has been proved that PCP-Dox can be easily and rapidly internalized by various cancer cells due to the strong interaction between multivalent choline phosphate (CP) groups and cell membranes. Furthermore, Dox, linked to the polymer carrier via acid-labile hydrazone bond, can be released from carriers due to the increased acidity in lysosome/endosome (pH 5.0-5.5) after the polymer prodrug was internalized into the cancer cells. The cell viability assay demonstrated that this novel polymer prodrug has shown enhanced cytotoxicity in various cancer cells, indicating its great potential as a new drug delivery system for cancer therapy.

Diester structure monomer, preparation method thereof and application

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Paragraph 0063-0070, (2021/02/10)

The invention provides a diester structure monomer, a preparation method thereof and application of an ArF photoresist formula. The preparation method of the diester structure monomer comprises the following steps of: dissolving glycolate in a reaction solvent to prepare a glycolate solution; mixing the glycolate solution with triethylamine in a protective atmosphere, and performing cooling to form a mixed solution; and keeping the protective atmosphere unchanged, and adding methacryloyl chloride into the mixed solution to carry out esterification reaction, thereby generating the diester structure monomer. According to the preparation method of the diester structure monomer, the generated diester structure monomer has a diester long side chain and a group with small size and high acid sensitivity; resin synthesized by the diester structure monomer is endowed with better adhesive force and film-forming property, deprotection reaction efficiency and plasticity, and the hardness and brittleness of the resin are improved. And the prepared diester acid protection structure monomer has the advantages of higher yield, low by-product content and easiness in separation and purification.

Method for preparing amphipathy star-like doxorubicin polymer prodrug

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Paragraph 0025, (2017/08/31)

The invention relates to the field of medicinal chemistry synthesis, in particular to a preparation method and application of an amphipathy star-like doxorubicin polymer prodrug. The preparation method of the amphipathy star-like doxorubicin polymer prodrug comprises the following steps: (1) synthesizing a star-like ATRP (Atom Transfer Radical Polymerization) initiator on the basis of cyclodextrin; (2) introducing a hydrophobic monomer with pH sensitivity through ATRP reaction; (3) introducing hydrophilic ethylene glycol methacrylate (OEGMA) through the ATRP reaction so as to obtain a star-like amphipathy polymer prodrug; (4) substituting an ester group at the tail end of MGMA by using amino of hydrazine hydrate; (5) further modifying doxorubicin by using amino on a polymer. The amphipathy star-like doxorubicin polymer prodrug has the advantages of being high in micelle stability, high in drug loading capacity, good in stimulation response control and the like, and the characteristics that water solubility of hydrophobic drug molecules and transferring of nano medicines are effectively solved.

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