133201-84-0

Upstream product

• 4643-20-3 (E)-4-chloro-3-buten-2-one 
• 1120-73-6 2-methyl-2-cyclopenten-1-one 
• 133319-29-6 (R_p)-(E)-But-2-enyl-tert-butylphenylphosphine oxide 
• 21448-79-3 (R)-tert-butylmethylphenylphosphine oxide 
• 133319-25-2 (S_p)-(E)-But-2-enyl-tert-butylphenylphosphine oxide 
• 38802-08-3 (S)-(-)-tert-butylmethylphenylphosphine oxide 
• 133201-85-1 4-((S)-tert-Butyl-phenyl-phosphinoyl)-butan-2-ol 
• 133201-85-1 4-((R)-tert-Butyl-phenyl-phosphinoyl)-butan-2-ol 

Downstream Products

• 133201-88-4 (1R,7aR)-1-[(R)-3-((S)-tert-Butyl-phenyl-phosphinoyl)-1-methyl-propyl]-7a-methyl-1,2,3,6,7,7a-hexahydro-inden-5-one 
• 133201-89-5 (1R,7aR)-1-[(E)-(S)-3-((S)-tert-Butyl-phenyl-phosphinoyl)-1-methyl-allyl]-7a-methyl-1,2,3,6,7,7a-hexahydro-inden-5-one 
• 133201-87-3 (2R,3R)-3-[(R)-3-((S)-tert-Butyl-phenyl-phosphinoyl)-1-methyl-propyl]-2-methyl-2-(3-oxo-butyl)-cyclopentanone 
• 133253-02-8 (2R,3R)-3-[(E)-(S)-3-((S)-tert-Butyl-phenyl-phosphinoyl)-1-methyl-allyl]-2-methyl-2-(3-oxo-butyl)-cyclopentanone 
• 133319-27-4 (1S,7aS)-1-[(S)-3-((R)-tert-Butyl-phenyl-phosphinoyl)-1-methyl-propyl]-7a-methyl-1,2,3,6,7,7a-hexahydro-inden-5-one 
• 133201-89-5 (1S,7aS)-1-[(E)-(R)-3-((R)-tert-Butyl-phenyl-phosphinoyl)-1-methyl-allyl]-7a-methyl-1,2,3,6,7,7a-hexahydro-inden-5-one 
• 133201-87-3 (2S,3S)-3-[(S)-3-((R)-tert-Butyl-phenyl-phosphinoyl)-1-methyl-propyl]-2-methyl-2-(3-oxo-butyl)-cyclopentanone 

Relevant academic research and scientific papers

The Preparation of (R)- and (S)-(E)-But-2-enyl-t-butylphenylphosphine Oxides and their Enantiospecific Conversion into Enantiomeric Hydrindenones related to Vitamin D

The individual enantiomers of (E)-but-2-enyl-t-butylphenylphosphine oxide have been prepared, and the lithiated carbanions of each undergo completely stereoselective conjugate addition with 2-methylcyclopent-2-enone to generate enolates, which upon reacti