133217-39-7

Basic information

• Product Name: Thiocarbonic acid O-chloromethyl ester S-phenyl ester
• Synonyms: Thiocarbonic acid O-chloromethyl ester S-phenyl ester
• CAS NO: 133217-39-7
• Molecular Weight: 202.661
• Mol File: 133217-39-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Thiocarbonic acid O-chloromethyl ester S-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Thiocarbonic acid O-chloromethyl ester S-phenyl ester(133217-39-7)
• EPA Substance Registry System: Thiocarbonic acid O-chloromethyl ester S-phenyl ester(133217-39-7)

Safety Data

• Hazardous Substances Data: 133217-39-7(Hazardous Substances Data)

Upstream product

• 22128-62-7 carbonochloridic acid, chloromethyl ester 
• 108-98-5 thiophenol 

Downstream Products

• 133217-57-9 Butyric acid phenylsulfanylcarbonyloxymethyl ester 
• 133217-44-4 Thiocarbonic acid O-iodomethyl ester S-phenyl ester 

Relevant articles and documents

Acyloxymethyl carbonochloridates. New intermediates in prodrug synthesis

The synthesis of a number of stable acyloxymethyl carbonochloridates 7 has been accomplished in four steps from chloromethyl carbonochloridate 3. Each step has been optimized with propanoyl-oxymethyl carbonochloridate 7c as a model compound (64% overall yield). Diethyl ether-boron trifluoride catalyzes the conversion of carbonothioate 6cc to the carbonochloridate 7c by chlorination with sulfuryl chloride. Acylation of a few compounds containing hydroxy or amino groups by 7c is described.