1332358-75-4Relevant academic research and scientific papers
Nickel-catalyzed reductive defunctionalization of esters in the absence of an external reductant: Activation of C-O bonds
Iyori, Yasuaki,Takahashi, Kenjiro,Yamazaki, Ken,Ano, Yusuke,Chatani, Naoto
supporting information, p. 13610 - 13613 (2019/11/14)
The nickel-catalyzed reductive cleavage of esters in the absence of an external reductant, which involves the cleavage of an inert acyl C-O bond in O-Alkyl esters is reported. Various groups, such as N-containing heterocycles, esters, amides, and even arene rings can function as a directing group.
Heterocyclic Compound
-
Paragraph 1825; 1826, (2018/06/15)
The present invention provide a compound having an orexin receptor antagonistic activity, which is expected to be useful as medicaments such as agents for the prophylaxis or treatment of sleep disorder, depression, anxiety disorder, panic disorder, schizophrenia, drug dependence, Alzheimer's disease and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
Palladium-catalyzed direct alkoxycarbonylation of aromatic C-H bonds via selective C-C cleavage of a-keto esters
Zhou, Wei,Li, Pinhua,Zhang, Yicheng,Wang, Lei
, p. 2343 - 2352 (2013/10/01)
A novel palladium-catalyzed direct alkoxycarbonylation of 2-arylpyridines, 2-arylquinolines, benzo[h]quinolines, 2-phenylpyrimidines, N-pyrimidine pyrroles and N-pyrimidine indoles via aromatic C-H bond activation and selective C-C cleavage of a-keto esters has been developed. The method has the advantages of wide functional group tolerance, high selectivity, broad range of substrates and good yields.
New reactivity of oxaziridine: Pd(II)-catalyzed aromatic C-H ethoxycarbonylation via C-C bond cleavage
Peng, Xingao,Zhu, Yingguang,Ramirez, Thomas A.,Zhao, Baoguo,Shi, Yian
supporting information; experimental part, p. 5244 - 5247 (2011/12/04)
A novel Pd(II)-catalyzed aromatic C-H ethoxycarbonylation with oxaziridine involving C-C bond cleavage is described. Various aromatic 2-phenylpyridines and related compounds as well as aryl ureas can be effectively ethoxycarbonylated. A catalytic cycle in
