1332365-10-2Relevant articles and documents
Development of a scalable synthesis of oxadiazole based S1P1 receptor agonists
Lukin, Kirill,Kishore, Vimal,Gordon, Thomas
, p. 666 - 671 (2013/06/27)
A robust and scalable synthesis was developed for the preparation of oxadiazole based S1P1 inhibitors. A new method for the separation of triphenylphosphine oxide from reaction products and an improved method for the synthesis of oxadiazoles in the presence of DBU were incorporated into the process to achieve its scalability.
NOVEL OXADIAZOLE COMPOUNDS
-
, (2011/06/26)
Novel oxadiazole compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions as agonists or antagonists of the S1P family of G protein-coupled receptors for treating diseases associated with modulation o