1332499-29-2

Upstream product

• 1332499-28-1 1-[2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-β-D-erythro-pentofuranosyl]-4-{[(di(n-butyl)amino)methylidene]amino}-3-(3-trifluoroacetamidoprop-1-yl)-1H-pyrazolo[3,4-d]pyrimidine 
• 102691-36-1 N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite 
• 1332499-25-8 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-3-(3-trifluoroacetamidoprop-1-yl)-1H-pyrazolo[3,4-d]pyrimidine 
• 1332499-26-9 1-(2-deoxy-β-D-erythro-pentofuranosyl)-4-{[(di-n-butylamino)methylidene]amino}-3-(3-trifluoroacetamidoprop-1-yl)-1H-pyrazolo[3,4-d]pyrimidine 
• 14719-21-2 trifluoroacetyl-propargyl amine 
• 187479-00-1 (2R,3S,5R)-5-(4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol 

Relevant academic research and scientific papers

A novel strategy of chemical modification for rate enhancement of 10-23 DNAzyme: A combination of A9 position and 8-aza-7-deaza-2′-deoxyadenosine analogs

With the help of a divalent-metal ion, 10-23 DNAzyme cleaves RNA. Chemical modification of its catalytic loop to make a more efficient enzyme has been a challenge. Our strategy started from its five 2′-deoxyadenosine residues (A5, A9, A11, A12, and A15) i