13325-10-5

Basic information

• Product Name: 4-Amino-1-butanol
• Synonyms: 1-Butanol, 4-amino-;4-aminobutan-1-ol;4-Aminobutanol-1;4-hdyroxybutylamine;4-hydroxybutanamine;H2NCH2(CH2)2CH2OH;NH2-(CH2)4-OH;N-ABU(4)-OL
• CAS NO: 13325-10-5
• Molecular Formula: C₄H₁₁NO
• Molecular Weight: 89.14
• EINECS: 236-364-4
• Product Categories: Miscellaneous;omega-Aminoalkanols;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;Amino Alcohols;Organic Building Blocks;Oxygen Compounds;Amino Alcohols;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
• Mol File: 13325-10-5.mol
• Article Data: 26

Chemical Properties

• Melting Point: 16-18 °C(lit.)
• Boiling Point: 206 °C(lit.)
• Flash Point: 226 °F
• Appearance: Clear colorless to slightly yellow/Liquid
• Density: 0.967 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0575mmHg at 25°C
• Refractive Index: n20/D ~1.462(lit.)
• Storage Temp.: Store at R.T.
• PKA: 15.10±0.10(Predicted)
• Water Solubility: MISCIBLE
• Sensitive: Air Sensitive & Hygroscopic
• BRN: 1731411
• CAS DataBase Reference: 4-Amino-1-butanol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-1-butanol(13325-10-5)
• EPA Substance Registry System: 4-Amino-1-butanol(13325-10-5)

Safety Data

• Hazard Codes: C
• Statements: 34-22
• Safety Statements: 26-36/37/39-45-25
• RIDADR: UN 2735 8/PG 3
• WGK Germany: 3
• F: 34
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 13325-10-5(Hazardous Substances Data)

Usage

Chemical Properties

Very light clear yellow liquid

Uses

Different sources of media describe the Uses of 13325-10-5 differently. You can refer to the following data:
1. 4-Amino-1-butanol is a useful intermediate in a variety of organic synthesis. It is mainly used in personal-care products, preparation of water soluble cationic flocculants and ion exchange resins as well as in the preparation of beta-lactam antibiotics. It is used for the production of efficient anionic emulsifiers, nonionic polyethylene emulsions, water treatment, metal treatment and absorption of carbon dioxide gas. It is used as a pigment dispersion aid and curing agent in selected textile -resins.
2. 4-Amino-1-butanol was used:As a linker in the synthesis of highly branched poly(β-amino esters)(HPAEs) for gene delivery.As a side chain to modulate antimicrobial and hemolytic activities of copolymers.In the total synthesis of (+)-fawcettimine,(+)-fawcettidine, and (?)-lycojapodine A.

InChI:InChI=1/C4H11NO/c5-3-1-2-4-6/h6H,1-5H2/p+1

Synthetic route

4-amino-n-butyric acid (56-12-2) → 4-Aminobutanol (13325-10-5)

Conditions	Yield
With sulfuric acid; hydrogen In water at 79.84℃; under 60006 Torr;	91.1%
With sodium tetrahydroborate; iodine In tetrahydrofuran

N-(4-hydroxybutyl)phthalimide (24697-70-9) → 4-Aminobutanol (13325-10-5)

Conditions	Yield
With water; sodium hydroxide at 100℃; for 10h;	90.8%

N-(4-acetyloxybutyl)phthalimide (7606-22-6) → 4-Aminobutanol (13325-10-5)

Conditions	Yield
With weakly basic anion exchange resin (DIAION WA-20); water In ethanol for 1h; Heating;	90%
With hydrazine hydrate
With sulfuric acid Heating;
With potassium hydroxide Heating;

ethanol (64-17-5) + sodium ethanolate (141-52-6) + 2-iminotetrahydrofuran hydrochloride (2453-49-8) → 4-Aminobutanol (13325-10-5)

Conditions	Yield
Hydrieren des Reaktionsprodukts;

ethene (74-85-1) → 4-Aminobutanol (13325-10-5)

Conditions	Yield
With hydrogenchloride; vanadium(III) sulfate; hydroxylamine hydrochloride

4-Chloro-1-butanol (928-51-8) → 4-Aminobutanol (13325-10-5)

Conditions	Yield
With ammonia at 40 - 50℃;
With ammonia

4-Chloro-1-butanol (928-51-8) → 4-Aminobutanol (13325-10-5) + 4,4’-azanediylbis(butan-1-ol) (79448-06-9)

Conditions	Yield
With ammonia

4-hydroxy-1-butanitrile (628-22-8) → 4-Aminobutanol (13325-10-5)

Conditions	Yield
With ethanol; nickel at 60℃; Hydrogenation;
With ethanol; sodium

3-cyano-propionic acid methyl ester (4107-62-4) → 4-Aminobutanol (13325-10-5)

Conditions	Yield
With lithium aluminium tetrahydride; diethyl ether

1-nitro-4-nitrosyloxy-butane → 4-Aminobutanol (13325-10-5)

Conditions	Yield
With hydrochloride of tin dichloride

3,6-dihydro-2H-[1,2]oxazine (3686-43-9) → 4-Aminobutanol (13325-10-5)

Conditions	Yield
With hydrogen; nickel In methanol

4-aminobut-2-yn-1-ol hydrochloride (39711-80-3) → 4-Aminobutanol (13325-10-5)

Conditions	Yield
With hydrogen; nickel In water under 760 Torr; Ambient temperature;

Butane-1,4-diol (110-63-4) → tetrahydrofuran (109-99-9) + pyrrolidine (123-75-1) + 4-Aminobutanol (13325-10-5)

Conditions	Yield
With ammonia; CrZMS-5 at 300℃; for 4h;	A n/a B 48.0 % Chromat. C n/a

N1-(4-hydroxybutyl)-N2-(p-nitrophenyl)formamidine (130340-72-6) → 4-Aminobutanol (13325-10-5) + p-nitroformanilide (16135-31-2)

Conditions	Yield
With water; acetic acid In tetrahydrofuran Ambient temperature; Yield given. Yields of byproduct given;

N-chloro-4-aminobutan-1-ol (153363-51-0) → 4-Aminobutanol (13325-10-5) + N,N-dichloro-4-amino-1-butanol

Conditions	Yield
In water at 25℃; Rate constant; Mechanism; Thermodynamic data; E(a);

3,6-dihydro-2H-[1,2]oxazine (3686-43-9) + methanol (67-56-1) + platinum → pyrrolidine (123-75-1) + 1,2-oxazinane (36652-42-3) + 4-Aminobutanol (13325-10-5)

Conditions	Yield
Hydrogenation;

4-chloro-butylamine hydrochloride → 4-Aminobutanol (13325-10-5)

Conditions	Yield
With water at 150℃;

<4-chloro-butyl>-acetate → 4-Aminobutanol (13325-10-5)

Conditions	Yield
With ammonia at 40 - 50℃;

1-nitro-4-nitrosyloxy-butane + HCl-salt tin dichloride → 4-Aminobutanol (13325-10-5)

N-<4-benzyloxy-butyl>-phthalimide → 4-Aminobutanol (13325-10-5)

Conditions	Yield
With potassium hydroxide

4-Chloro-1-butanol (928-51-8) + ammonia (7664-41-7) → 4-Aminobutanol (13325-10-5) + 4,4’-azanediylbis(butan-1-ol) (79448-06-9)

Conditions	Yield
at 20℃;

hydrogenchloride (7647-01-0) + ethene (74-85-1) + hydroxylamine hydrochloride + vanadium(III)-sulfate → 4-Aminobutanol (13325-10-5) + ethylamine (75-04-7) + ethanolamine (141-43-5) + N-butylamine (109-73-9)

N-butylamine (109-73-9) → 4-Aminobutanol (13325-10-5) + 4-amino-butan-2-ol (114963-62-1, 127912-49-6, 39884-48-5)

Conditions	Yield
With potassium tetrachloroplatinate; copper dichloride In water at 160℃; for 10h; Title compound not separated from byproducts.;

CH2CHCH2CH2NH2BH3 (1039627-16-1) → 4-Aminobutanol (13325-10-5) + 4-amino-butan-2-ol (114963-62-1, 127912-49-6, 39884-48-5)

Conditions	Yield
Stage #1: CH2CHCH2CH2NH2BH3 With iodine In dichloromethane at 20℃; Stage #2: With sodium hydroxide; dihydrogen peroxide In methanol; water at 20℃; regioselective reaction;

Br(1-)*C15H25N2O(1+) (1180496-62-1) → 4-Aminobutanol (13325-10-5) + (4-formylbenzyl)trimethylammonium bromide (1180496-61-0)

Conditions	Yield
at 25℃; pH=11.8; Equilibrium constant; aq. phosphate buffer;

Butane-1,4-diol (110-63-4) → pyrrolidine (123-75-1) + 1-pyrroline (5724-81-2) + 4-Aminobutanol (13325-10-5) + 1,4-diaminobutane (110-60-1)

Conditions	Yield
With ammonia; chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II) In para-xylene at 180℃; under 38253.8 Torr; for 12h; Product distribution / selectivity; Autoclave; Inert atmosphere;
With ammonia; chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II) In toluene at 155℃; under 38253.8 Torr; for 24h; Product distribution / selectivity; Autoclave; Inert atmosphere;
With chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II); ammonia at 180℃; for 12h; Temperature; Inert atmosphere; Autoclave;
With chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II); ammonia In toluene at 155℃; under 30153 Torr; for 24h; Catalytic behavior; Pressure; Reagent/catalyst; Temperature; Autoclave; Inert atmosphere;
With chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II); ammonia In toluene at 155℃; under 31503.2 Torr; for 12h; Inert atmosphere; Autoclave;

Butane-1,4-diol (110-63-4) → 4-Aminobutanol (13325-10-5) + 1,4-diaminobutane (110-60-1)

Conditions	Yield
With ammonia; chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II) In toluene at 155℃; under 30753.1 Torr; for 12h; Product distribution / selectivity; Autoclave;
With ammonia; hydrogen; chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II) In toluene at 180℃; under 52505.3 Torr; for 12h; Product distribution / selectivity; Cooling; Autoclave;
With ammonia; chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II) In toluene at 155℃; under 30753.1 Torr; for 12h; Product distribution / selectivity; Autoclave;

Butane-1,4-diol (110-63-4) → 4-Aminobutanol (13325-10-5)

Conditions	Yield
With ammonia; (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In toluene at 155℃; under 33753.4 Torr; for 12h; Product distribution / selectivity; Autoclave;
With ammonia; hydrogen; (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In toluene at 155℃; under 33753.4 Torr; for 12h; Product distribution / selectivity; Cooling; Autoclave;
With ammonia; (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); 1,1,1-tris(diethylphosphinomethyl)ethane In toluene at 155℃; under 29252.9 Torr; for 12h; Product distribution / selectivity; Inert atmosphere;

Butane-1,4-diol (110-63-4) → pyrrolidine (123-75-1) + 1-pyrroline (5724-81-2) + 4-Aminobutanol (13325-10-5)

Conditions	Yield
With ammonia; (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); bis(2-diphenylphosphinoethyl)phenylphosphine In toluene at 155℃; under 28502.9 Torr; for 12h; Product distribution / selectivity; Inert atmosphere;
With (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); ammonia; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine] at 155℃; for 12h; Temperature; Inert atmosphere; Autoclave;
With (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); ammonia; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In toluene at 155℃; under 33753.4 Torr; for 12h; Inert atmosphere; Autoclave;
With (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); ammonia; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine] In toluene at 155℃; under 36753.7 Torr; for 12h; Pressure; Reagent/catalyst; Autoclave; Inert atmosphere;

phthalic anhydride (85-44-9) + 4-Aminobutanol (13325-10-5) → N-(4-hydroxybutyl)phthalimide (24697-70-9)

Conditions	Yield
at 145℃; for 0.5h;	100%
In toluene for 3h; Reflux;	99%
In toluene for 3h; Heating;	98%

4-Aminobutanol (13325-10-5) + di-tert-butyl dicarbonate (24424-99-5) → (4-hydroxybutyl)carbamic acid tert-butyl ester (75178-87-9)

Conditions	Yield
With triethylamine In dichloromethane for 10h; Inert atmosphere;	100%
In chloroform	100%
With triethylamine In acetonitrile at 0℃; for 6.5h; Inert atmosphere;	100%

4-Aminobutanol (13325-10-5) + 4-hydroxy-4-methylhex-2-ynenitrile (32837-88-0) → 4-[5-Amino-2-ethyl-2-methyl-furan-(3E)-ylideneamino]-butan-1-ol (89376-05-6)

Conditions	Yield
In dichloromethane at 0℃; for 3h;	100%

4-Aminobutanol (13325-10-5) + 4-Ethyl-4-hydroxyhex-2-ynenitrile (107291-76-9) → 4-[5-Amino-2,2-diethyl-furan-(3E)-ylideneamino]-butan-1-ol (89376-11-4)

Conditions	Yield
In dichloromethane at 0℃; for 3h;	100%

4-Aminobutanol (13325-10-5) + 4-chloro-benzoyl chloride (122-01-0) → 4-chloro-N-(4-hydroxybutyl)benzamide (130340-60-2)

Conditions	Yield
With sodium hydroxide In chloroform; water for 0.75h; Cooling with ice;	100%
Stage #1: 4-chloro-benzoyl chloride With pyridine; Merrifield's resin-bound 6-methyl-2-thiouracil In dichloromethane at 80℃; for 0.0833333h; microwave irradiation; Stage #2: 4-Aminobutanol In dichloromethane at 80℃; for 0.0833333h; microwave irradiation;	70%
With triethylamine at 0℃;

4-Aminobutanol (13325-10-5) + benzyl chloroformate (501-53-1) → benzyl 4-hydroxybutylcarbamate (17996-13-3)

Conditions	Yield
With sodium carbonate In tetrahydrofuran; water at 0 - 20℃;	100%
With tetrabutylammomium bromide at 20℃; for 0.0833333h;	99%
With tetrapropylammonium L-prolinate at 20℃; for 2h;	96%

4-Aminobutanol (13325-10-5) + 4-ethoxy-3-nitropyridine (1796-84-5) → 3-nitro-4-<(4-hydroxy-1-butyl)amino>pyridine (94751-21-0)

Conditions	Yield
at 120℃; for 0.0333333h;	100%

4-Aminobutanol (13325-10-5) + tert-butyldimethylsilyl chloride (18162-48-6) → (4-{[tert-butyl(dimethyl)silyl]oxy}butyl)amine (245660-15-5)

Conditions	Yield
With pyridine for 12h; Inert atmosphere;	100%
With pyridine In dichloromethane for 12h;	100%
With pyridine at 20℃; for 16h; Inert atmosphere;	100%

4-Aminobutanol (13325-10-5) + N,N'-bis-Boc-S-methyl-isothiourea (322474-21-5) → N2,N3-bis(tert-butoxycarbonyl)-N1-(4-hydroxybutyl)guanidine (208465-10-5)

Conditions	Yield
In tetrahydrofuran at 50℃; for 2h;	100%
In N,N-dimethyl-formamide at 20℃; for 3.5h;	97.3%
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃;	95%

4-Aminobutanol (13325-10-5) → 1-chloro-4-aminobutane hydrochloride

Conditions	Yield
With thionyl chloride In toluene at 20℃; for 1h;	100%
With thionyl chloride In toluene at 80℃; for 17h; Inert atmosphere;	93%
With thionyl chloride at 0 - 50℃;

N-(Benzyloxycarbonyloxy)succinimide (13139-17-8) + 4-Aminobutanol (13325-10-5) → benzyl 4-hydroxybutylcarbamate (17996-13-3)

Conditions	Yield
With sodium hydrogencarbonate In water; acetone at 20℃; for 4h;	100%
With triethylamine In acetone at 20℃; for 7h;	92.8%

4-Aminobutanol (13325-10-5) + N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide (82911-69-1) → (9H-fluoren-9-yl)methyl (4-hydroxybutyl)carbamate (209115-32-2)

Conditions	Yield
With pyridine In methanol at 23℃; for 23h;	100%
In tetrahydrofuran; water at 20℃; Cooling with ice;	1.21 g

4-butanolide (96-48-0) + 4-Aminobutanol (13325-10-5) → 4-hydroxy-N-(4-hydroxybutyl)butanamide

Conditions	Yield
In 5,5-dimethyl-1,3-cyclohexadiene Reflux;	100%
In various solvent(s) for 18h; Heating;

4-Aminobutanol (13325-10-5) + formic acid ethyl ester (109-94-4) → N-(4-hydroxybutyl)formamide (174656-73-6)

Conditions	Yield
Reflux;	100%
for 6h; Heating / reflux;	79%
In ethanol for 18h; Reflux;	62.4%

4-Aminobutanol (13325-10-5) + acetone (67-64-1) → 4-hydroxy-N-isopropylbutan-1-amine (42042-71-7)

Conditions	Yield
With platinum(IV) oxide; hydrogen In ethanol at 20℃; for 48h;	100%
With palladium 10% on activated carbon; hydrogen In ethanol under 7500.75 Torr;	100%
With hydrogen; platinum(IV) oxide In ethanol at 20℃; under 1520.1 - 2280.15 Torr; for 48h;	147.64 g
With hydrogen; platinum(IV) oxide In ethanol under 1520.1 - 2280.15 Torr; for 48h;
With platinum(IV) oxide; hydrogen at 20℃; for 168h;

4-Aminobutanol (13325-10-5) + cyclopentanone (120-92-3) → 4-(cyclopentylamino)-1-butanol

Conditions	Yield
With hydrogen; platinum(IV) oxide In ethanol at 20℃; under 1520.1 - 2280.15 Torr; for 48h;	100%
With platinum(IV) oxide; hydrogen In ethanol at 20℃; for 48h;	100%

4-Aminobutanol (13325-10-5) + 3,5-di-tert-butyl-2-hydroxybenzaldehyde (37942-07-7) → (E)-2,4-di-tert-butyl-6-(((4-hydroxybutyl)imino)methyl)phenol (1243265-04-4)

Conditions	Yield
In methanol Reflux; Inert atmosphere;	100%

4-Aminobutanol (13325-10-5) + ethyl trifluoroacetate, (383-63-1) → 2,2,2-trifluoro-N-(4-hydroxy-butyl)-acetamide (128238-43-7)

Conditions	Yield
In ethanol at 20℃;	100%
at 0 - 20℃;	100%
In methanol at 0℃;	100%
at 0℃; for 2h;	99%

4-Aminobutanol (13325-10-5) + benzaldehyde (100-52-7) → 3-(benzylamino)propan-1-ol (4720-29-0)

Conditions	Yield
Stage #1: 4-Aminobutanol; benzaldehyde In methanol at 20℃; for 0.166667h; Stage #2: With sodium tetrahydroborate In methanol at 0 - 20℃;	100%

4-Aminobutanol (13325-10-5) + 2,4-dichlorobenzoyl chloride (89-75-8) → 2,4-dichloro-N-(4-hydroxybutyl)benzamide

Conditions	Yield
With sodium hydroxide In chloroform; water for 0.75h; Cooling with ice;	100%

4-Aminobutanol (13325-10-5) + p-Tolylisocyanate (622-58-2) → N-(4-hydroxybutyl)-N'-(4-tolyl) urea (452917-19-0)

Conditions	Yield
In dichloromethane at 0 - 12℃; for 3.5h;	99.9%

4-Aminobutanol (13325-10-5) + 2,6-dimethylphenylisothiocyanate (19241-16-8) → 1-(2,6-Dimethyl-phenyl)-3-(4-hydroxy-butyl)-thiourea

Conditions	Yield
In acetone 1.) room temperature, 1 d, 2.) reflux;	99%

quinoline-2-carboxylic acid (93-10-7) + 4-Aminobutanol (13325-10-5) → N-[1-(4-hydroxy)butyl]quinoline-2-carboxamide (600709-78-2)

Conditions	Yield
Stage #1: quinoline-2-carboxylic acid With 1-hydroxybenzotriazol-hydrate; dicyclohexyl-carbodiimide In dichloromethane at 20℃; Stage #2: 4-Aminobutanol In dichloromethane at 20℃;	99%

4-chloro-5,6-(difuran-2-yl)furo[2,3-d]pyrimidine (912273-18-8) + 4-Aminobutanol (13325-10-5) → 4-[(5,6-di-(2-furyl)-furo[2,3-d]pyrimidin-4-yl)amino]butan-1-ol

Conditions	Yield
In propan-1-ol for 24h; Heating;	99%

4-Aminobutanol (13325-10-5) + 4-tolyl iodide (624-31-7) → 4-(p-tolylamino)butan-1-ol

Conditions	Yield
With 2-(2-methyl-1-oxopropane)cyclohexanone; caesium carbonate; copper(l) iodide In N,N-dimethyl-formamide at 20℃; for 16h;	99%
With copper(l) iodide; 2-(2-methyl-1-oxopropane)cyclohexanone; caesium carbonate In N,N-dimethyl-formamide at 20℃; for 16h; Schlenk technique; Sealed tube;	99%

2,4-dichloropyrido[2,3-d]pyrimidine (126728-20-9) + 4-Aminobutanol (13325-10-5) → N,N'-bis(4-hydroxybutyl)pyrido[2,3-d]pyrimidine-2,4-diamine hydrochloride

Conditions	Yield
With triethylamine In ethanol at 70℃; for 5h;	99%

phthalic anhydride (85-44-9) + 4-Aminobutanol (13325-10-5) → 2-(2-phthalimidoethoxy)ethanol (69676-63-7)

Conditions	Yield
In toluene for 6h; Reflux; Dean-Stark;	99%

4-Aminobutanol (13325-10-5) + benzoic acid (65-85-0) → N-(4-hydroxybutyl)benzamide (102877-79-2)

Conditions	Yield
Stage #1: benzoic acid With benzotriazol-1-ol; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 1h; Inert atmosphere; Stage #2: 4-Aminobutanol In dichloromethane at 20℃; for 12h;	99%

2,4-dichloro-N-(2,6-dichlorophenyl)pyrimidine-5-carboxamide (835633-83-5) + 4-Aminobutanol (13325-10-5) → 2-chloro-1-(2,6-dichlorophenyl)-4-((4-hydroxybutyl)amino)pyrimidine-5-carboxamide

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃; for 0.5h;	99%

Upstream product

• 110-63-4 Butane-1,4-diol 
• 7647-01-0 hydrogenchloride 
• 74-85-1 ethene 
• 542-56-3 nitrous acid isobutyl ester 
• 24697-70-9 N-(4-hydroxybutyl)phthalimide 
• 56-12-2 4-amino-n-butyric acid 
• 1180496-62-1 Br^(1-)*C₁₅H₂₅N₂O⁽¹⁺⁾ 
• 1039627-16-1 CH₂CHCH₂CH₂NH₂BH₃ 
• 109-73-9 N-butylamine 
• 928-51-8 4-Chloro-1-butanol 
• 7664-41-7 ammonia 
• 3686-43-9 3,6-dihydro-2H-[1,2]oxazine 
• 67-56-1 methanol 
• 153363-51-0 N-chloro-4-aminobutan-1-ol 

Downstream Products

• 24697-70-9 N-(4-hydroxybutyl)phthalimide 
• 123-75-1 pyrrolidine 
• 14253-36-2 N-(4-hydroxy-butyl)-N'-phenyl-urea 
• 109475-02-7 4-(2-methyl-5-phenyl-pyrrol-1-yl)-butan-1-ol 
• 59801-41-1 4-(1,1-dioxo-1λ⁶-thiomorpholin-4-yl)-butan-1-ol 
• 92432-61-6 N-<3,5-Dimethoxy-4-hydroxy-benzoyl>-N'-<δ-hydroxy-butyl>-guanidin 
• 103416-94-0 5-Hydroxy-2-(4-hydroxy-butyl)-isoindole-1,3-dione 
• 123-13-7 N-(1-hexyl) pyrrolidine 
• 93160-49-7 4-<4-Butylmercapto-3-methyl-benzyloxy>-butylamin 
• 92111-95-0 4-<3-Methyl-4-methylmercapto-benzyloxy>-butylamin 
• 245660-15-5 (4-{[tert-butyl(dimethyl)silyl]oxy}butyl)amine 
• 739342-23-5 3-(benzyloxy)-2-ethyl-1-(4-hydroxybutyl)pyridin-4(1H)-one 
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• 99858-57-8 4-{[1-Phenyl-meth-(E)-ylidene]-amino}-butan-1-ol 

Related news

Equilibrium solubility of carbon dioxide in aqueous solutions of 3-amino-1-propanol, 4-Amino-1-butanol (cas 13325-10-5) and 5-amino-1-pentanol at low partial pressures07/19/2019

Vapor liquid equilibrium (VLE) data of CO2 solubility in aqueous amine solutions are essential for solving problems associated with flue gas purification. This work presents new VLE data of 3-amino-1-propanol, 4-amino-1-butanol and 5-amino-1-pentanol, respectively. An equilibrium cell, connected...detailed

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Catalytic hydrogenation of amino acids to amino alcohols with complete retention of configuration

Rh-MoOx/SiO2 is an effective heterogeneous catalyst for selective hydrogenation of amino acids to amino alcohols in a water solvent. MoOx modification of Rh drastically enhanced the activity and improved the selectivity and ee. Various amino alcohols were obtained in high yields (90-94%) with complete retention of configuration. This journal is the Partner Organisations 2014.

Preparation method of 4-aminobutanol

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A 4 - amino - 1 - butanol synthetic method

The invention discloses a synthetic method of 4-animo-1-butanol. The synthetic method is characterized by comprising the following steps: reacting a raw material A in an acid solution to obtain an intermediate product B, carrying out contact reaction on the intermediate product B and a raw material C in the presence of alkaline substances to obtain an intermediate product D, and transforming the intermediate product D into the target product, namely 4-animo-1-butanol, in the presence of a reducing agent. The synthetic method is suitable for large-scale synthesis, synthesis steps are short, and the operation is convenient.