133256-59-4

Usage

Uses

Used in Coordination Chemistry:
Me6TREN is used as a ligand for coordination complexes, due to its ability to bind to metal ions and form stable complexes. This property makes it a valuable component in the development of new coordination compounds with potential applications in various fields.
Used in Catalysis:
Me6TREN has been studied for its potential applications in catalysis. Its ability to bind to metal ions and form stable complexes can enhance the catalytic activity of metal catalysts, leading to improved reaction efficiency and selectivity.
Used in Drug Delivery:
Me6TREN has been explored for its potential use in drug delivery systems. Its ability to form stable complexes with metal ions can be utilized to improve the solubility, stability, and targeted delivery of therapeutic agents, potentially enhancing their efficacy and reducing side effects.
Used in Materials Science:
Me6TREN has also been studied for its potential applications in materials science. Its unique cage-like structure and ability to form stable complexes with metal ions can contribute to the development of new materials with tailored properties for various applications.

InChI:InChI=1/C12H27N3/c1-13-7-4-9-14(2)11-6-12-15(3)10-5-8-13/h4-12H2,1-3H3

Upstream product

• 50-00-0 formaldehyd 
• 294-80-4 1,5,9-triazacyclododecane 
• 35980-62-2 1,5,9-triazacyclododecane trihydrobromide 
• 3030-47-5 N,N,N',N'',N'''-pentamethyldiethylenetriamine 
• 41203-22-9 1,4,8,11-tetramethyl-1,4,8,11-tetra-azacyclotetradecane 

Downstream Products

• 3083-10-1 1,1,4,7,10,10-hexamethyltriethylenetetramine 
• 3030-47-5 N,N,N',N'',N'''-pentamethyldiethylenetriamine 
• 41203-22-9 1,4,8,11-tetramethyl-1,4,8,11-tetra-azacyclotetradecane 

Relevant academic research and scientific papers

Chloro(N,N′,N″-trimethyl-1,5,9-triazacyclododecane-κ 3N)zinc(II) hexafluorophosphate

The preparation and crystal structure of [ZnCl(C12H27-N3)]PF6 are described. The Zn atom has a tetrahedral environment, coordinated to three N atoms of the triaza macrocyclic ligand and to one Cl- ion. The Zn - N distances are in the range 2.037 (1)-2.048 (1) A, with Zn - Cl 2.2010 (4) A.

Method for preparing alkoxyamines from nitroxides

The invention relates to a process for preparing alkoxyamines. This process consists in mixing, in an organic solvent, a metal salt, a ligand for the metal, a halocarbon compound ZX and a nitroxide, in keeping the reaction medium stirring at a temperature of between 20° C. and 90° C. until the nitroxide has disappeared, in recovering the organic phase, in washing it with water and then in isolating the alkoxyamine by evaporating the organic solvent under reduced pressure.

Coordination to RMg+ and RZn+ cations

Addition of a second coordinating agent (coord*) to a solution of RM(coord)+A- (R = ethyl or neopentyl, M = Zn or Mg, A- = 1,2,3,4-tetraphenylcyclopentadienyl) can provide equilibrium mixtures of these compounds, coord, and RM(coord*)+A-. This exchange with RMg(coord)+ requires the addition of a small amount of R2Mg, but added R2Zn is not necessary for exchanges with RZn(coord)+. The equilibrium constants provide information about the relative abilities of different coordinating agents to coordinate to RM+ and reveal significant differences between coordination to RMg+ and RZn+. Reactions of RM(coord)+ with R′2M (R = ethyl or neopentyl for RMg(coord)+ and ethyl, isopropyl, tert-butyl, neopentyl, or p-methylphenyl for RZn(coord)+) provide equilibrium mixtures of these components, R′M(coord)+, and R2M. The equilibrium constants provide information about the effect of R on stability. An X-ray structure of p-methylphenylzinc(2,5,8,11-tetramethyl-2,5,8,11-tetraazadodecane)+ shows that just three of the N atoms are coordinated to Zn. The effects of coord, R, and metal on RM(coord)+ stability are discussed, and the abilities of coordinating agents to coordinate to RM+, to slow allylic isomerization of (CH2 double bond CMeCH2)2Zn, and to convert R2Zn to RZn(coord)+ are compared.

New Synthetic Routes to Macrocyclic Triamines

1,5,9-Triazacyclododecane and related macrocyclic triamines can be conveniently constructed around a single carbon atom as a template; this route permits the preparation of selectively alkylated derivatives.

Fragmentation During the Formic Acid/Formaldehyde (Eschweiler-Clarke) Methylation of Polyamines

Eschweiler-Clarke methylations of both acyclic and cyclic polyamines can lead to methylation products of fragments of the original polyamine; thus 1,5,9,13-tetra-azatridecane yields 1,1,3,3-tetramethylpropanediamine exclusively and 1,5,9-triazacyclododecane gives 45 percent 1,5,9-trimethyl-1,5,9-triazacyclododecane and 45 percent 2,6,10-trimethyl-2,6,10-triazaundecane.