1332587-47-9Relevant academic research and scientific papers
A novel Friedlander-type synthesis of 3-aryl quinolines from 3-oxo-2,3-diaryl-propionaldehydes
Luo, Wanrong,Mu, Qiuchao,Qiu, Wenwei,Liu, Ting,Yang, Fan,Liu, Xiaofeng,Tang, Jie
supporting information; experimental part, p. 7090 - 7095 (2011/10/07)
3-Aryl quinolines are readily synthesized by a novel Friedlaender-type reaction with 3-oxo-2,3-diaryl-propionaldehydes and 2-amino arylaldehydes. A preliminary mechanism of this novel one pot, two-step synthesis has been explored with the proofs of isolation of the enaminone intermediate and the eliminated benzoic acid in this reaction.
