133261-10-6

Basic information

• Product Name: ETHYL 3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLATE
• Synonyms: BUTTPARK 62\11-02;ETHYL 3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLATE;Ethyl 3-(tert-butyl)-1-methyl-1H-pyrazole-5-carboxylate, tech;5-TERT-BUTYL-2-METHYL-2H-PYRAZOLE-3-CARBOXYLIC ACID ETHYL ESTER;ETHYL 3-(TERT-BUTYL)-1-METHYLPYRAZOLE-5-CARBOXYLATE;1H-Pyrazole-5-carboxylicacid, 3-(1,1-dimethylethyl)-1-methyl-, ethyl ester;-1-methyl-1H-pyrazole-5-carboxylate
• CAS NO: 133261-10-6
• Molecular Formula: C₁₁H₁₈N₂O₂
• Molecular Weight: 210.27
• Mol File: 133261-10-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 116°C 15mm
• Flash Point: 134.8°C
• Appearance: /
• Density: 1.04g/cm³
• Vapor Pressure: 0.00121mmHg at 25°C
• Refractive Index: 1.502
• CAS DataBase Reference: ETHYL 3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLATE(133261-10-6)
• EPA Substance Registry System: ETHYL 3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLATE(133261-10-6)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 133261-10-6(Hazardous Substances Data)

Usage

General Description

ETHYL 3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLATE is a chemical compound with the molecular formula C12H19N3O2. It is a pyrazole derivative with a carboxylic ester group, and it is commonly used as a building block in organic synthesis. This chemical has applications in pharmaceutical and agricultural industries as a synthetic intermediate for various compounds. It is important to handle this compound with care and adhere to safety protocols, as it may pose risks to human health and the environment if not used properly.

InChI:InChI=1/C11H18N2O2/c1-6-15-10(14)8-7-9(11(2,3)4)12-13(8)5/h7H,6H2,1-5H3

Upstream product

• 13395-36-3 ethyl trimethylacetopyruvate 
• 60-34-4 methylhydrazine 
• 77-78-1 dimethyl sulfate 
• 83405-70-3 ethyl 3-(tert-butyl)-1H-pyrazole-5-carboxylate 
• 75-97-8 3,3-dimethyl-butan-2-one 

Downstream Products

• 1332875-06-5 8-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-methyl-2-(2-trifluoromethyl-phenyl)-7H-purine 
• 1332875-04-3 5-tert-butyl-4-chloro-2-methyl-2H-pyrazole-3-carboxylic acid [6-methyl-5-nitro-2-(2-trifluoromethyl-phenyl)-pyrimidin-4-yl]-amide 
• 1332875-39-4 2-[2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-trifluoromethyl-phenyl)-3H-imidazo[4,5-c]pyridin-4-yloxy]-ethanol 
• 1332875-48-5 [2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-trifluoromethyl-phenyl)-3H-imidazo[4,5-c]pyridin-4-yloxy]-acetic acid 
• 1332875-49-6 [2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-trifluoromethyl-phenyl)-3H-imidazo[4,5-c]pyridin-4-yloxy]-acetaldehyde 
• 1332875-95-2 2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-5-(2-chloro-phenyl)-1H-imidazo[4,5-b]pyridine 
• 1332875-97-4 5-tert-butyl-4-chloro-2-methyl-2H-pyrazole-3-carboxylic acid [6-(2-chloro-phenyl)-3-nitro-pyridin-2-yl]-amide 
• 1332876-27-3 5-tert-butyl-4-chloro-2-methyl-2H-pyrazole-3-carboxylic acid [6-(2-chloro-phenyl)-2-methoxy-3-nitro-pyridin-4-yl]-amide 
• 1332877-05-0 N-(3-amino-6-(2-chlorophenyl)-2-methoxypyridin-4-yl)-3-tert-butyl-4-chloro-1-methyl-1H-pyrazole-5-carboxamide 
• 1332875-00-9 2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-7-chloro-5-(2-trifluoromethyl-phenyl)-1H-imidazo[4,5-b]pyridine 
• 1332875-53-2 {2-[2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-trifluoromethyl-phenyl)-3H-imidazo[4,5-c]pyridin-4-yloxy]-ethyl}-dimethyl-amine 
• 1392516-97-0 2-(5-tert-butyl-2-methyl-2H-pyrazol-3-yl)-5-(2-difluoromethoxyphenyl)-1H-benzimidazole 
• 1392517-56-4 2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-5-(2,6-difluoro-phenyl)-1H-benzimidazole 
• 1392517-54-2 5-tert-butyl-4-chloro-2-methyl-2H-pyrazole-3-carboxylic acid (2',6'-difluoro-3-nitro-biphenyl-4-yl)-amide 

Relevant articles and documents

SUBSTITUTED BENZIMDAZOLE DERIVATIVES USEFUL AS TRPM8 RECEPTOR MODULATORS

The present invention is directed to benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by TRP M8, including for example, inflammatory pain, inflammatory hyperalgesia

PYRAZOLEPYRIMIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE and INFLAMMATORY DISEASES

The present invention relates to compounds that are inhibitors of PDElA, a phosphodiesterase that is involved in the modulation of the degradation of cartilage, joint degeneration and diseases involving such degradation and/or inflammation, and particular