1332634-79-3

Upstream product

• 450-91-9 4-fluoro-2-methoxyaniline 
• 832113-96-9 methyl 4-chloro-5-methylthieno[2,3-d]pyrimidine-6-carboxylate 
• 1332761-22-4 4-(4-fluoro-2-methoxy-phenylamino)-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester 

Downstream Products

• 1332712-59-0 4-[4-Fluoro-2-(1-methanesulfonyl-pyrrolidin-3-yloxy)-phenylamino]-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester 
• 1332759-41-7 methyl 4-(4-fluoro-2-((tetrahydro-2H-pyran-4-yl)methoxy)phenylamino)-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylate 
• 1332759-64-4 4-[2-(1-Ethylcarbamoyl-ethoxy)-4-fluoro-phenylamino]-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester 
• 1332759-65-5 4-(2-(1-(Ethylamino)-1-oxopropan-2-yloxy)-4-fluorophenylamino)-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid 
• 1332760-70-9 4-{2-[1-(3-tert-Butoxycarbonylamino-propylcarbamoyl)-ethoxy]-4-fluoro-phenylamino}-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester 
• 1332760-73-2 4-{2-[1-(3-Amino-propylcarbamoyl)-ethoxy]-4-fluoro-phenylamino}-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid (2-hydroxy-ethyl)-amide 
• 1332759-42-8 4-(4-fluoro-2-((tetrahydro-2H-pyran-4-yl)methoxy)phenylamino)-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid 
• 1332759-43-9 N-(3-(dimethylamino)propyl)-4-(4-fluoro-2-((tetrahydro-2H-pyran-4-yl)methoxy)phenylamino)-5-methyl-thieno[2,3-d]pyrimidine-6-carboxamide 
• 1332759-70-2 C₂₀H₁₇FN₄O₃S 
• 1332759-83-7 C₂₅H₂₉FN₆O₂S 
• 1332760-71-0 4-{2-[1-(3-amino-propylcarbamoyl)ethoxy]-4-fluoro-phenylamino}-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester 
• 1332760-72-1 4-{2-[1-(3-tert-butoxycarbonylamino-propylcarbamoyl)ethoxy]-4-fluoro-phenylamino}-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid 
• 1332758-81-2 Methyl 4-(2-(2-(tert-butoxycarbonylamino)ethoxy)-4-fluorophenylamino)-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylate 
• 1332712-38-5 4-[2-((R)-1-tert-Butoxycarbonyl-pyrrolidin-3-yloxy)-4-fluoro-phenylamino]-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester 

Relevant academic research and scientific papers

THIENOPYRIMIDINES CONTAINING A SUBSTITUTED ALKYL GROUP FOR PHARMACEUTICAL COMPOSITIONS

The present invention relates to novel thienopyhmidine compounds of general formula pharmaceutical compositions comprising these compounds and their therapeutic use for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof.

THIENOPYRIMIDINES CONTAINING A SUBSTITUTED ALKYL GROUP FOR PHARMACEUTICAL COMPOSITIONS

The present invention relates to novel thienopyrimidine compounds of general formula pharmaceutical compositions comprising these compounds and their therapeutic use for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof.