1332641-33-4

Upstream product

• 99695-34-8 (1R,2S,3S,4R)-2,3,4-tri-O-benzyl-5-(benzyloxymethyl)-cyclohex-5-ene-1,2,3,4-tetrol 
• 1332641-35-6 2,3,4,6-tetra-O-benzyl-5a-carba-β-D-xylo-hex-5(5a)-enopyranosyl bromide 

Downstream Products

• 1333124-16-5 methyl 6-[2,3,4,6-tetra-O-benzyl-5a-carba-β-D-xylo-hex-5(5a)-enopyranosylamino]-2,3,4-tri-O-benzyl-6-deoxy-α-D-glucopyranoside 
• 1332641-39-0 C₆₃H₆₇NO₉ 
• 1332641-38-9 methyl 3-[2,3,4,6-tetra-O-benzyl-5a-carba-α-D-xylo-hex-5(5a)-enopyranosylamino]-4,6-O-benzylidene-3-deoxy-α-D-mannopyranoside 
• 1332641-37-8 methyl 3-[2,3,4,6-tetra-O-benzyl-5a-carba-α-D-xylo-hex-5(5a)-enopyranosylamino]-4,6-Obenzylidene-3-deoxy-α-D-glucopyranoside 
• 1332641-45-8 methyl 3-[5a-carba-α-D-xylo-hex-5(5a)-enopyranosylamino]-3-deoxy-α-D-mannopyranoside 
• 1332641-43-6 methyl 3-[5a-carba-α-D-xylo-hex-5(5a)-enopyranosylamino]-3-deoxy-α-D-glucopyranoside 
• 1332641-35-6 2,3,4,6-tetra-O-benzyl-5a-carba-β-D-xylo-hex-5(5a)-enopyranosyl bromide 

Relevant academic research and scientific papers

Synthesis and α-Glucosidase II inhibitory activity of valienamine pseudodisaccharides relevant to N-glycan biosynthesis

Valienol-derived allylic C-1 bromides have been used as carbaglycosyl donors for α-xylo configured valienamine pseudodisaccharide synthesis. We synthesised valienamine analogues of the Glc(α1→3)Glc and Glc(α1→3)Man disaccharides representing the linkages

Investigation of coupling reactions for the synthesis of valienamine pseudodisaccharides

Amine-linked pseudodisaccharides based on vali-enamine were synthesised by C-N bond-forming reactions between valienol-derived C-1 electrophiles and carbohydrate nitrogen nucleophiles. Palladium-catalysed coupling with trichloroacetimidate leaving groups, Mitsunobu reactions with a nosylamide nucleophile, and alkylation of amines by C-1 bromides were investigated.