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1332708-05-0

C16H19ClN4O is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1332708-05-0 Structure

  • Basic information

    1. Product Name: C16H19ClN4O
    2. Synonyms: C16H19ClN4O
    3. CAS NO:1332708-05-0
    4. Molecular Formula:
    5. Molecular Weight: 318.806
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1332708-05-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C16H19ClN4O(CAS DataBase Reference)
    10. NIST Chemistry Reference: C16H19ClN4O(1332708-05-0)
    11. EPA Substance Registry System: C16H19ClN4O(1332708-05-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1332708-05-0(Hazardous Substances Data)

1332708-05-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1332708-05-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,3,2,7,0 and 8 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1332708-05:
(9*1)+(8*3)+(7*3)+(6*2)+(5*7)+(4*0)+(3*8)+(2*0)+(1*5)=130
130 % 10 = 0
So 1332708-05-0 is a valid CAS Registry Number.

1332708-05-0Downstream Products

1332708-05-0Relevant articles and documents

Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel

Ryckmans, Thomas,Aubdool, Aisah A.,Bodkin, Jennifer V.,Cox, Peter,Brain, Susan D.,Dupont, Thomas,Fairman, Emma,Hashizume, Yoshinobu,Ishii, Naoko,Kato, Teruhisa,Kitching, Linda,Newman, Julie,Omoto, Kiyoyuki,Rawson, David,Strover, Jade

, p. 4857 - 4859 (2011)

TrpA1 is an ion channel involved in nociceptive and inflammatory pain. It is implicated in the detection of chemical irritants through covalent binding to a cysteine-rich intracellular region of the protein. While performing an HTS of the Pfizer chemical collection, a class of pyrimidines emerged as a non-reactive, non-covalently binding family of agonists of the rat and human TrpA1 channel. Given the issues identified with the reference agonist Mustard Oil (MO) in screening, a new, non-covalently binding agonist was optimized and proved to be a superior agent to MO for screening purposes. Compound 16a (PF-4840154) is a potent, selective agonist of the rat and human TrpA1 channel and elicited TrpA1-mediated nocifensive behaviour in mouse.

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