133271-21-3

Basic information

• Product Name: 2(1H)-Pyrimidinone, 5-(1,1-dimethylethyl)- (9CI)
• Synonyms: 2(1H)-Pyrimidinone, 5-(1,1-dimethylethyl)- (9CI);5-tert-butylpyrimidin-2(1H)-one
• CAS NO: 133271-21-3
• Molecular Formula: C8H12N2O
• Molecular Weight: 152.19368
• Product Categories: PYRIMIDINE
• Mol File: 133271-21-3.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2(1H)-Pyrimidinone, 5-(1,1-dimethylethyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Pyrimidinone, 5-(1,1-dimethylethyl)- (9CI)(133271-21-3)
• EPA Substance Registry System: 2(1H)-Pyrimidinone, 5-(1,1-dimethylethyl)- (9CI)(133271-21-3)

Safety Data

• Hazardous Substances Data: 133271-21-3(Hazardous Substances Data)

Usage

Category

Heterocyclic organic compound

Uses

Pharmaceutical intermediate in drug development and synthesis processes

Structure

Pyrimidine ring with a tertiary butyl group attached to the 5-position of the ring

Medicinal Properties

Potential medicinal properties, studied for its role in various biological processes

Handling Precautions

Handle and use with caution due to potential health hazards and environmental impacts.

Upstream product

• 54045-32-8 tert-butyl-malonaldehyde (Z)-enol tautomer 
• 57-13-6 urea 
• 4210-60-0 t-butylmalonodinitrile 
• 55740-28-8 2-(tert-butyl)malonaldehyde 
• 88905-15-1 2-[1-Hydroxy-meth-(E)-ylidene]-3,3-dimethyl-butyraldehyde 

Downstream Products

• 156777-81-0 5-tert-butyl-2-chloropyrimidine 

Relevant articles and documents

PYRIDAZINONES AS PARP7 INHIBITORS

The present invention relates to pyridazinones and related compounds which are inhibitors of PARP7 and are useful in the treatment of cancer.

PYRIMIDINE-SUBSTITUTED PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

The invention relates to new pyrrolidine derivatives of the formula wherein R1 to R3, Ar, L T and n are as defined in the description and claims, to their use as medicaments, to methods for their therapeutic use and to pharmaceutical

NEW AZIRIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE AS ACETYL-COA CARBOXYLASE INHIBITORS

The invention relates to new azetidine derivatives of the formula (I) wherein Ar1, Ar2, X, R, T and L are as defined in the description, to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.