133271-21-3Relevant academic research and scientific papers
PYRIDAZINONES AS PARP7 INHIBITORS
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Paragraph 2072, (2019/11/11)
The present invention relates to pyridazinones and related compounds which are inhibitors of PARP7 and are useful in the treatment of cancer.
PYRIMIDINE-SUBSTITUTED PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
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Page/Page column 90, (2014/11/11)
The invention relates to new pyrrolidine derivatives of the formula (I), wherein R1 to R3, Ar, L T and n are as defined in the description and claims, to their use as medicaments, to methods for their therapeutic use and to pharmaceu
PYRIMIDINE-SUBSTITUTED PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
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Paragraph 0366; 0371, (2014/10/29)
The invention relates to new pyrrolidine derivatives of the formula wherein R1 to R3, Ar, L T and n are as defined in the description and claims, to their use as medicaments, to methods for their therapeutic use and to pharmaceutical
AZETIDINE DERIVATIVES
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Paragraph 0652, (2013/06/28)
Azetidine derivatives of which the following is exemplary and their use in the treatment of obesity, diabetes or dyslipidemia.
NEW AZIRIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE AS ACETYL-COA CARBOXYLASE INHIBITORS
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Page/Page column 103, (2013/07/05)
The invention relates to new azetidine derivatives of the formula (I) wherein Ar1, Ar2, X, R, T and L are as defined in the description, to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.
The Synthesis of Some Lipophilic Tetradentate Ligands for Use in the Formation of Metal-Linked Polymers
Crossley, Maxwell J.,Gorjian, Sargon,Sternhell, Sever,Tansey, Kerrie M.
, p. 723 - 738 (2007/10/02)
Two lipophilic tetradentate ligands, 5,5'-di-t-butyl- and 5,5'-dihexyl-2,2'-bipyrimidine, were prepared via either Ullmann or nickel(0)-promoted reactions in low but useful yields.Approaches towards the synthesis of lipophilic ligands based on 2,2'-biimidazole, namely 4,4',5,5'-tetrabutyl-2,2'-biimidazole (from decane-4,5-dione) and various 4,4',5,5'-tetra(arylamino)-2,2'-biimidazoles (from 4,4',5,5'-tetrabromo-2,2'-biimidazole and arylamines), and a 2,2'-bibenzimidazole, 5,5',6,6'-tetra(octyloxy)-2,2'-bibenzimidazole (from N,N'-bisoxamide), were uniformly unsuccessful for preparing the 2,2'-biheteroaryl compounds.
