1332832-84-4Relevant articles and documents
Synthesis of N-acyl-N,O-acetals from N-aryl amides and acetals in the presence of TMSOTf
Downey, C. Wade,Fleisher, Alan S.,Rague, James T.,Safran, Chelsea L.,Venable, Megan E.,Pike, Robert D.
supporting information; experimental part, p. 4756 - 4759 (2011/10/05)
Secondary amides undergo in situ silyl imidate formation mediated by TMSOTf and an amine base, followed by addition to acetal acceptors to provide N-acyl-N,O-acetals in good yields. An analogous, high-yielding reaction is observed with 2-mercaptothiazolin