133295-83-7Relevant academic research and scientific papers
Angular Hydroxymethylation of Functionalized Decalin Systems
Chan, T. H.,Schwerdtfeger, A. E.
, p. 3294 - 3298 (2007/10/02)
Functionalized β-dicarbonyl bicyclic compounds 5 and 17 were hydroxymethylated at the angular position as the (benzyloxy)methoxy derivatives with diisopropylethylamine (DIPEA) and benzyl chloromethyl ether in the presence of paraformaldehyde.The stereochemistry of cis-8a-methyl>-3-(phenylthio)-4a,5,6,8a-tetrahydronaphthalene-1,8(4H,7H)-dione (12) was confirmed by X-ray analysis of the ethylene ketal 16.
