1332981-48-2Relevant academic research and scientific papers
Synthesis and preliminary evaluation of a modified estradiol-core bearing a fused γ-lactone as non-estrogenic inhibitor of 17β-hydroxysteroid dehydrogenase type 1
Ouellet, Etienne,Ayan, Diana,Poirier, Donald
, p. 5510 - 5513 (2011/10/12)
A non-estrogenic inhibitor of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) was designed based on a modified 3-hydroxy-estra-1,3,5(10)- triene core having an additional five-member lactone ring and a benzamide group. The inhibitor was synthesized, fu
