133305-92-7Relevant academic research and scientific papers
New Bronchodilators. 1. 1,5-Substituted 1H-Imidazoquinolin-4(5H)ones
Suzuki, Fumio,Kuroda, Takeshi,Nakasato, Yoshisuke,Manabe, Haruhiko,Ohmori, Kenji,et al.
, p. 4045 - 4053 (2007/10/02)
A series of novel xanthine-based tricyclic heterocycles in 1H-imidazoquinolin-4(5H)-ones was designed, synthesized, and tested as potential active bronchodilators.Inhibition of the Schulz-Dale (SD) reaction-induced contraction in trachea and inhibi
SYNTHESIS OF 1H-IMIDAZOQUINOLIN-4(5H)-ONE VIA PALLADIUM-CATALYZED CYCLIZATION OF N-(2-BROMOPHENYL)-1H-IMIDAZOLE-4-CARBOXAMIDE
Kuroda, Takeshi,Suzuki, Fumio
, p. 6915 - 6918 (2007/10/02)
A new heterocycle, 5-butyl-1-methyl-1H-imidazolequinolin-4(5H)-one has been synthesized using palladium-catalyzed cyclization.A yield of the cyclization was optimized by changing base, additive and reaction temperature.
Imidazoquinolone derivatives
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, (2008/06/13)
Novel imidazoquinolone derivative represented by the formula (I); STR1 wherein R1 represents hydrogen, alkyl, cycloalkyl, alkenyl aralkyl, aralkenyl or substituted or unsubstituted aryl; X represents nitrogen or STR2 where R2 is hydr
