133305-95-0Relevant articles and documents
New Bronchodilators. 1. 1,5-Substituted 1H-Imidazoquinolin-4(5H)ones
Suzuki, Fumio,Kuroda, Takeshi,Nakasato, Yoshisuke,Manabe, Haruhiko,Ohmori, Kenji,et al.
, p. 4045 - 4053 (2007/10/02)
A series of novel xanthine-based tricyclic heterocycles in 1H-imidazoquinolin-4(5H)-ones was designed, synthesized, and tested as potential active bronchodilators.Inhibition of the Schulz-Dale (SD) reaction-induced contraction in trachea and inhibi