1333077-69-2Relevant academic research and scientific papers
Synthesis of cytimidine through a one-pot copper-mediated amidation cascade
Serrano, Catherine M.,Looper, Ryan E.
, p. 5000 - 5003 (2011/11/13)
A concise synthesis of cytimidine was developed utilizing tandem Cu-mediated N-aryl amidations followed by global deprotection. This sequence exploits a regioselective coupling of an iodobenzamide with a halopyrimidine that allows the union of three fragments in a single synthetic manipulation and will permit the efficient and rapid diversification of the cytimidine core.
