133308-49-3Relevant academic research and scientific papers
Iridium-Catalyzed Asymmetric Hydrogenation of 2H-Chromenes: A Highly Enantioselective Approach to Isoflavan Derivatives
Xia, Jingzhao,Nie, Yu,Yang, Guoqiang,Liu, Yangang,Zhang, Wanbin
supporting information, p. 4884 - 4887 (2017/09/23)
A highly efficient (aS)-Ir/In-BiphPHOX-catalyzed asymmetric hydrogenation of substituted 2H-chromenes and substituted benzo[e][1,2]oxathiine 2,2-dioxides is described. A series of 2H-chromenes and benzo[e][1,2]oxathiine 2,2-dioxides were hydrogenated to give the target products in high yields (92-99%) with excellent enantioselectivities (up to 99.7% ee) using our catalytic system. This reaction provides a direct and efficient method for the construction of chiral benzo six-membered oxygen-containing compounds.
Synthesis and antirhinovirus activity of cyano and amidino substituted flavanoids
Conti,Desideri,Orsi,Sestili,Stein
, p. 725 - 730 (2007/10/02)
Cyano and amidino flavans, isoflavans and 3(2H)-isoflavenes were synthesized in order to study their in vitro antirhinovirus activity, by comparison with the known corresponding chloro derivatives. The activity of the new compounds was evaluated on rhinov
