1333141-24-4Relevant articles and documents
Synthesis and biological evaluation of 5-fluoroquinolone-3-carboxylic acids as potential HIV-1 integrase inhibitors
He, Qiu-Qin,Zhang, Xuan,Yang, Liu-Meng,Zheng, Yong-Tang,Chen, Fener
, p. 671 - 676 (2013/07/26)
A series of new quinolone-3-carboxylic acids as HIV-1 integrase inhibitors featuring a fluorine atom at C-5 position were synthesized and evaluated for their antiviral activity in C8166 cell culture. These newly synthesized compounds showed anti-HIV activ
Structural modifications of quinolone-3-carboxylic acids with anti-HIV activity
He, Qiu-Qin,Gu, Shuang-Xi,Liu, Jia,Wu, Hai-Qiu,Zhang, Xuan,Yang, Liu-Meng,Zheng, Yong-Tang,Chen, Fen-Er
, p. 5039 - 5045 (2011/10/03)
A series of new quinolone-3-carboxylic acids featuring a hydroxyl group at C-5 position were synthesized and evaluated for their in vitro activity against HIV in C8166 cell culture. All the compounds showed anti-HIV-1 activity with low micromolar to submi