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133319-36-5

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  • (S)-3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-hydroxy-propionic acid

    Cas No: 133319-36-5

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133319-36-5 Usage

General Description

(S)-3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-hydroxy-propionic acid, also known as (S)-3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-hydroxypropionic acid, is a chemical compound with a molecular formula of C11H9NO6. It is a specific isomer of 3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropanoic acid, which is used in the synthesis of various pharmaceuticals and other organic compounds. This chemical has potential applications in drug development and medical research due to its unique structural features and potential biological activities. Additionally, it has been studied for its potential use as a chiral building block in organic synthesis. More research is required to fully understand its potential uses and impacts in various fields.

Check Digit Verification of cas no

The CAS Registry Mumber 133319-36-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,3,1 and 9 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 133319-36:
(8*1)+(7*3)+(6*3)+(5*3)+(4*1)+(3*9)+(2*3)+(1*6)=105
105 % 10 = 5
So 133319-36-5 is a valid CAS Registry Number.

133319-36-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-3-(1,3-dioxoisoindol-2-yl)-2-hydroxypropanoic acid

1.2 Other means of identification

Product number -
Other names (S)-3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-hydroxy-propanoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:133319-36-5 SDS

133319-36-5Downstream Products

133319-36-5Relevant articles and documents

Enantioselective Synthesis of L- and D-Isoserine via Asymmetric Hydrogenation of Methyl N-Phthaloyl-3-amino-2-oxopropanoate

Nozaki, Kyoko,Sato, Naomasa,Takaya, Hidemasa

, p. 2179 - 2182 (1993)

L- and D-isoserine were synthesized enantioselectively via asymmetric hydrogenation of 3-amino-2-oxoester 5 catalyzed by Cl.Recrystallization and deprotection of (S)-6 (81percent ee) afforded enantiomerically pure L-isoserine.The enantioface selection by the catalyst was opposite to that observed in asymmetric hydrogenation of other 2-oxoesters, such as methyl phenylglyoxylate and methyl 2-oxocyclohexylacetate.

Novel method for synthesizing N-substituted phthalic anhydride-(S)-isoserine

-

Paragraph 0055; 0057; 0060; 0063; 0066; 0069; 0072; 0075, (2018/10/11)

The invention provides a low-cost method for synthesizing N-substituted phthalic anhydride-(S)-isoserine. The method comprises the following two steps: (1) taking (R)-(-)-3-chloro-1,2-propanediol as astarting raw material to carry out a Gabriel reaction with phthalimide to generate an intermediate (S)-2-(2,3-dyhydroxy-propyl)-isoindole-1,3-dione; and (2) oxidizing the primary alcohol groups in the intermediate (S)-2-(2,3-dyhydroxy-propyl)-isoindole-1,3-dione to carboxyl groups by using a water solution of sodium hypochlorite under the catalyst of a nitrogen oxide of tetramethylpiperidine toprepare the N-substituted phthalic anhydride-(S)-isoserine. Through the method, the use of an expensive raw material (S)-isoserine is avoided, the raw materials are cheap and easily available, the cost is low, the product purity is high, the impurity content is low, and the method is a novel process which can realize industrial production.

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